BMJ Case Rep . Urticaria and Angioedema as a Prodromal Cutaneous Manifestation of SARS-CoV-2 (COVID-19) Infection

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BMJ Case Rep


. 2020 Jul 7;13(7):e236981.
doi: 10.1136/bcr-2020-236981.
Urticaria and Angioedema as a Prodromal Cutaneous Manifestation of SARS-CoV-2 (COVID-19) Infection


Khalid Hassan ^{1 2}



Affiliations

• PMID: 32641443
• DOI: 10.1136/bcr-2020-236981

Abstract

This is a case of a patient who presented with an urticarial rash 48 hours before developing symptoms of fever and a continuous cough. She subsequently developed angioedema of her lips and hands before testing positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Urticarial rashes occurring 48 hours before other symptoms of COVID-19 infection have been documented. This case demonstrates the importance of heightened awareness that not all urticarial rashes represent spontaneous urticaria and as a consequence, this may result in misdiagnosis and ultimately delayed diagnosis. This is the first reported case in the literature of urticaria with angioedema as a prodromal phenomenon of COVID-19.

Keywords: Infectious diseases; dermatology; primary care.