Pediatr Infect Dis J . PEDIATRIC INFLAMMATORY MULTISYSTEM SYNDROME WITH CENTRAL NERVOUS SYSTEM INVOLVEMENT AND HYPOCOMPLEMENTEMIA FOLLOWING SARS-COV-2 INFECTION

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Pediatr Infect Dis J


. 2020 Jun 24.
doi: 10.1097/INF.0000000000002804. Online ahead of print.
PEDIATRIC INFLAMMATORY MULTISYSTEM SYNDROME WITH CENTRAL NERVOUS SYSTEM INVOLVEMENT AND HYPOCOMPLEMENTEMIA FOLLOWING SARS-COV-2 INFECTION


Tslil Regev ¹ , Maayan Antebi ¹ , Danny Eytan ^{2 3} , Yael Shachor-Meyouhas ⁴ , Anat Ilivitzki ^{3 5} , Yonatan Butbul Aviel ^{3 6 7} , Josef Ben-Ari ²



Affiliations

• PMID: 32639461
• DOI: 10.1097/INF.0000000000002804

Abstract

Pediatric inflammatory multisystem syndromes associated with Severe Acute Respiratory Syndrome Coronavirus 2 are emerging in recent reports. We describe a patient with critical illness consistent with atypical Kawasaki disease with cardiac dysfunction and abdominal involvement presenting weeks after Severe Acute Respiratory Syndrome Coronavirus 2 infection. Our patient showed unique central nervous system involvement with small vessel vasculitis and profound hypocomplementemia, both not previously reported in case descriptions and may hint at possible disease mechanisms.