J Eur Acad Dermatol Venereol . An Unusual Case of Bullous Hemorrhagic Vasculitis in a COVID-19 Patient

[tetano]

J Eur Acad Dermatol Venereol


. 2020 Jun 19.
doi: 10.1111/jdv.16760. Online ahead of print.
An Unusual Case of Bullous Hemorrhagic Vasculitis in a COVID-19 Patient


S Negrini ¹ , A Guadagno ² , M Greco ¹ , A Parodi ³ , M Burlando ³



Affiliations

• PMID: 32558979
• DOI: 10.1111/jdv.16760

Abstract

A novel Coronavirus strain, named "Severe Acute Respiratory Syndrome Coronavirus 2" (SARS-CoV-2) was recently identified as the etiological agent of the COronaVIrus Disease 2019 (COVID-19). Interestingly, a consistent number of COVID-19-associated skin manifestations seem to share a certain degree of vascular damage as common pathogenetic mechanism¹ . Vascular injury may be due to the direct damage of endothelial cells by the virus or may represents an epiphenomenon of a dysregulated host inflammatory responses triggered by the infection² . Here, we describe an unprecedented case of leukocytoclastic vasculitis presenting with a hemorrhagic bullous eruption in a patient affected by COVID-19.

Keywords: COVID-19; cutaneous; cutaneous manifestations; skin.