Am J Perinatol . The Impact of COVID-19 Infection on Labor and Delivery, Newborn Nursery, and Neonatal Intensive Care Unit: Prospective Observational Data From a Single Hospital System

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Am J Perinatol


. 2020 Jun 13.
doi: 10.1055/s-0040-1713416. Online ahead of print.
The Impact of COVID-19 Infection on Labor and Delivery, Newborn Nursery, and Neonatal Intensive Care Unit: Prospective Observational Data From a Single Hospital System


Ian Griffin ^{1 2 3} , Farah Benarba ⁴ , Caryn Peters ^{1 3} , Yinka Oyelese ⁵ , Tom Murphy ^{1 3} , Diana Contreras ⁴ , Christina Gagliardo ¹ , Eberechi Nwaobasi-Iwuh ¹ , M Cecilia DiPentima ¹ , Andrew Schenkman ^{1 2 3}



Affiliations

• PMID: 32534458
• DOI: 10.1055/s-0040-1713416

Abstract

Objective: Since its emergence in late 2019, severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), the novel coronavirus that causes novel coronavirus disease 2019 (COVID-19), has spread globally. Within the United States, some of the most affected regions have been New York, and Northern New Jersey. Our objective is to describe the impact of COVID-19 in a large delivery service in Northern New Jersey, including its effects on labor and delivery (L&D), the newborn nursery, and the neonatal intensive care unit (NICU).
Materials and methods: Between April 21, 2020 and May 5, 2020, a total of 78 mothers (3.6% of deliveries) were identified by screening history or examination to either be COVID-19 positive or possible positives (persons under investigation). Of the mothers who were tested after admission to L&D, 28% tested positive for SARS-CoV-2.
Discussion: Isolation between mother and infant was recommended in 62 cases, either because the mother was positive for SARS-CoV-2 or because the test was still pending. Fifty-four families (87%) agreed to isolation and separation. The majority of infants, 51 (94%), were initially isolated on the newborn nursery. Six needed NICU admission. No infants had clinical evidence of symptomatic COVID-19 infection. Fourteen infants whose mothers were positive for SARS-CoV-2, and who had been separated from the mother at birth were tested for SARS-CoV-2 postnatally. All were negative.
Results: COVID-19 posed a significant burden to mothers, infants, and staff over the 5-week study period. The yield from screening mothers for COVID-19 on L&D was high. Most families accepted the need for postnatal isolation and separation of mother and newborn.
Conclusion: Our study suggests that the transmission of SARS-CoV-2 from mother to her fetus/newborn seems to be uncommon if appropriate separation measures are performed at birth.
Key points: ? The yield of targeted testing for SARS-CoV-2, on mothers on Labor and Delivery is high.. ? Agreement to separation of mothers and infants to reduce transmission of SARS-CoV-2 was high.. ? The incidence of symptomatic COVID-19 in newborns is low, if appropriate separation occurs at birth..