J Med Virol
. 2020 Jun 4.
doi: 10.1002/jmv.26134. Online ahead of print.
Pancreatic Injury in the Course of Coronavirus Disease 2019 (COVID-19): A Not-So-Rare Occurrence
Giuseppe Bruno 1 , Claudia Fabrizio 1 , Carmen Rita Santoro 1 , Giovanni Battista Buccoliero 1
Affiliations
- PMID: 32497298
- DOI: 10.1002/jmv.26134
Abstract
Despite respiratory symptoms are typically found during the course of coronavirus disease 2019 (COVID-19), gastrointestinal manifestations are increasingly described. However, data regarding COVID-19-associated pancreatic injury are still limited, as well as the mechanisms underlying COVID-19 induced-pancreatic damage have not been completely clarified. Herein, we described pancreatic abnormalities in six (8.5%) out of 70 patients with COVID-19 hospitalized in our unit from February 25, 2020 to May 10, 2020. We hypothesized that pancreatic damage may be associated with several factors including direct effect of SARS-CoV-2, inflammatory cascade, dehydration and multiple organ dysfunction. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; increased lipase; pancreatic injury.