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World Neurosurg COVID-19-associated Encephalitis Mimicking Glial Tumor: A Case Report

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  • World Neurosurg COVID-19-associated Encephalitis Mimicking Glial Tumor: A Case Report


    World Neurosurg


    . 2020 May 29;S1878-8750(20)31165-7.
    doi: 10.1016/j.wneu.2020.05.194. Online ahead of print.
    COVID-19-associated Encephalitis Mimicking Glial Tumor: A Case Report


    Ibrahim Efecan Efe 1 , Orhun Utku Aydin 1 , Alper Alabulut 2 , Ozgur Celik 2 , Kerameddin Aydin 3



    Affiliations

    Abstract

    Background: Reports on neurologic manifestations of coronavirus disease 2019 (COVID-19) have attracted broad attention. We present the unusual case of COVID-19-associated encephalitis mimicking a glial tumor.
    Case description: A 35-year-old woman presented with headache and seizures. T2 fluid-attenuated inverse recovery imaging showed hyperintensities in the left temporal lobe. Magnetic resonance spectroscopy showed an elevated choline peak. Imaging findings were suggestive of high-grade glioma. Antiepileptic medication failed to achieve seizure control. Left anterior temporal lobectomy was performed. The patient had no post-operative deficits and her symptoms completely improved. Histological examination revealed encephalitis. Post-operatively, our patient was tested positive for COVID-19.
    Conclusions: Our case raises awareness of neurologic manifestations of the disease and their potential to mimic glial tumors. For prompt diagnosis and prevention of transmission, clinicians should consider COVID-19 in patients with similar presentation.

    Keywords: COVID-19; SARS-CoV-2; coronavirus; encephalitis; spectroscopy.

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