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Biomed Pharmacother
. 2020 May 13;127:110230.
doi: 10.1016/j.biopha.2020.110230. Online ahead of print.
Advances in the Relationship Between Coronavirus Infection and Cardiovascular Diseases
Mengmeng Zhao 1 , Menglong Wang 1 , Jishou Zhang 1 , Jing Ye 1 , Yao Xu 1 , Zhen Wang 1 , Di Ye 1 , Jianfang Liu 1 , Jun Wan 2
Affiliations
- PMID: 32428835
- DOI: 10.1016/j.biopha.2020.110230
Abstract
The outbreak of coronavirus disease 2019 (COVID-19) has once again aroused people's concern about coronavirus. Seven human coronaviruses (HCoVs) have been discovered so far, including HCoV-229E, HCoV-NL63, HCoV-OC43, HCoV-HKU115, severe acute respiratory syndrome coronavirus, Middle East respiratory syndrome coronavirus and severe acute respiratory syndrome coronavirus 2. Existing studies show that the cardiovascular disease increased the incidence and severity of coronavirus infection. At the same time, myocardial injury caused by coronavirus infection is one of the main factors contributing to poor prognosis. In this review, the recent clinical findings about the relationship between coronaviruses and cardiovascular diseases and the underlying pathophysiological mechanisms are discussed. This review aimed to provide assistance for the prevention and treatment of COVID-19.
Keywords: Cardiovascular disease; Coronavirus; Coronavirus disease 2019; Middle East respiratory syndrome coronavirus; Severe acute respiratory syndrome coronavirus.