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Dtsch Med Wochenschr Coronavirus (SARS-CoV-2) - Outbreak in North Rhine-Westphalia (District of Heinsberg) - First Diagnosis of a COVID-19 Manifestation in a Couple

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  • Dtsch Med Wochenschr Coronavirus (SARS-CoV-2) - Outbreak in North Rhine-Westphalia (District of Heinsberg) - First Diagnosis of a COVID-19 Manifestation in a Couple


    Dtsch Med Wochenschr


    . 2020 May;145(10):665-669.
    doi: 10.1055/a-1163-1335. Epub 2020 May 19.
    [Coronavirus (SARS-CoV-2) - Outbreak in North Rhine-Westphalia (District of Heinsberg) - First Diagnosis of a COVID-19 Manifestation in a Couple]


    [Article in German]

    Jendrik Laufs 1 , Harry Elsbernd 2 , Friedrich H?lzl 3 , Klaus-Dieter Winter 1



    Affiliations

    Abstract

    in English , German
    History and clinical findings: Up to February 24th 2020 occasionally occuring SARS-CoV-2 infections in Germany without severe course. Emergency presentation of a couple in the emergency room. For seven days now, the man has fever, dry cough und physical weakness and the wife has similar symptoms of a milder form. The clinical examination shows fine crackles over both lungs and a respiratory failure of the husband.
    Investigations and diagnosis: Laboratory increase in inflammation parameters as well as transaminases and lactate dehydrogenase. Radiologically lung infiltrates of different severity. Further on diagnosis of a SARS-CoV-2-infection of both patients with a severe course of the male.
    Treatment and course: Intubation and mechanical ventilation of the male patient with prolonged intenive care treatment. Recovery of the female patient under conventional oxygen therapy.
    Discussion: These two cases show the starting point of an endemic spread of SARS-CoV-2 in the district of Heinsberg (North Rhine-Westphalia) and up to this point the first case of a life-threatenning course in Germany.


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