Am J Transplant. Novel Coronavirus (SARS-CoV-2) Infection in A Renal Transplant Recipient: Case Report

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Am J Transplant. 2020 Apr 10. doi: 10.1111/ajt.15897. [Epub ahead of print]
Novel Coronavirus (SARS-CoV-2) Infection in A Renal Transplant Recipient: Case Report.


Ning L¹, Liu L¹, Li W¹, Liu H¹, Wang J¹, Yao Z¹, Zhang S¹, Zhao D¹, Nashan B¹, Shen A¹, Liu L¹, Li L¹.

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Abstract

An ongoing outbreak of pneumonia associated with the severe acute respiratory coronavirus 2 (SARS-CoV-2) started in Wuhan, China, with cases now confirmed in multiple countries. The clinical course of patients remains to be fully characterized, clinical presentation ranges from asymptomatic infection to acute respiratory distress syndrome and acute renal failure，no pharmacological therapies of proven efficacy yet exist. We report a case of SARS-CoV-2 infection in a renal transplant recipient with excellent outcome. This case states the importance of close monitoring of the concentration of ciclosporin in patients treated with lopinavir/ritonavir, routine treatment of corticosteroid can be continued. This is a rare report of SARS-CoV-2 infection in a renal transplant recipient. Further data are needed to achieve better understanding of the impact of immunosuppressive therapy on the clinical presentation, severity and outcome of SARS-CoV-2 infections in solid organ transplant recipients.
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PMID:32277555DOI:10.1111/ajt.15897