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Am J Transplant. 2020 Apr 10. doi: 10.1111/ajt.15909. [Epub ahead of print]
Fatal outcome in a liver transplant recipient with COVID-19.
Huang JF1, Zheng KI2, George J3, Gao HN4, Wei RN5, Yan HD6, Zheng MH2,7,8.
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Abstract
Liver injury is common in patients with COVID-19, but little is known about its clinical presentation and severity in the context of liver transplantation. We describe a case of COVID-19 in a patient who had transplantation three years previously for hepatocellular carcinoma. The patient came to clinic with symptoms of respiratory disease; pharyngeal swabs for severe acute respiratory syndrome coronavirus 2 were positive. His disease progressed rapidly from mild to critical illness and was complicated by several nosocomial infections and multi-organ failure. Despite multiple invasive procedures and rescue therapies, he succumbed to the disease. The management of COVID-19 in the post-transplant setting presents complex challenges emphasizing the importance of strict prevention strategies.
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KEYWORDS:
COVID-19; liver; transplantation
PMID:32277591DOI:10.1111/ajt.15909