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Clin Infect Dis . Long-term outcome of short-course high-dose glucocorticoids for SARS: a 17-year follow-up in SARS survivors

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  • Clin Infect Dis . Long-term outcome of short-course high-dose glucocorticoids for SARS: a 17-year follow-up in SARS survivors


    Clin Infect Dis


    . 2020 Jul 16;ciaa992.
    doi: 10.1093/cid/ciaa992. Online ahead of print.
    Long-term outcome of short-course high-dose glucocorticoids for SARS: a 17-year follow-up in SARS survivors


    Chor-Wing Sing 1 , Kathryn C B Tan 2 , Ian C K Wong 1 3 , Bernard M Y Cheung 2 , Ching-Lung Cheung 1



    Affiliations

    Abstract

    Use of high-dose glucocorticoids for coronavirus disease 2019 (COVID-19; caused by SARS-CoV-2) is controversial because of safety concerns. We examined long-term consequences in severe acute respiratory syndrome (SARS; caused by SARS-CoV-1) survivors. Results showed that high-dose glucocorticoids greatly increased long-term risk of avascular necrosis, but not other major diseases.


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