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Open Forum Infect Dis
. 2023 May 9;10(5):ofad253.
doi: 10.1093/ofid/ofad253. eCollection 2023 May. Prevalence of SARS-CoV-2 Viremia in Presymptomatic Blood Donors in the Delta and Omicron Variant Eras
Paula Saá 1 , Rebecca V Fink 2 , Hina Dawar 3 , Clara Di Germanio 3 4 , Leilani Montalvo 3 , David J Wright 2 , David E Krysztof 1 , Steven H Kleinman 5 , Theresa Nester 6 , Debra A Kessler 7 , Rebecca L Townsend 1 , Bryan R Spencer 1 , Hany Kamel 8 , Jackie Vannoy 8 , Michael P Busch 3 4 , Susan L Stramer 1 , Mars Stone 3 4 , Philip J Norris 3 4 9 ; NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-Pediatric (REDS-IV-P)
Affiliations
Presymptomatic plasma samples from 1596 donors reporting coronavirus disease 2019 infection or symptoms after blood donation were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA and anti-S and anti-N antibodies. Prior infection and vaccination both protected from developing SARS-CoV-2 RNAemia and from symptomatic infection. RNAemia rates did not differ in the Delta and Omicron variant eras.
Keywords: COVID-19; vaccination; viremia.
. 2023 May 9;10(5):ofad253.
doi: 10.1093/ofid/ofad253. eCollection 2023 May. Prevalence of SARS-CoV-2 Viremia in Presymptomatic Blood Donors in the Delta and Omicron Variant Eras
Paula Saá 1 , Rebecca V Fink 2 , Hina Dawar 3 , Clara Di Germanio 3 4 , Leilani Montalvo 3 , David J Wright 2 , David E Krysztof 1 , Steven H Kleinman 5 , Theresa Nester 6 , Debra A Kessler 7 , Rebecca L Townsend 1 , Bryan R Spencer 1 , Hany Kamel 8 , Jackie Vannoy 8 , Michael P Busch 3 4 , Susan L Stramer 1 , Mars Stone 3 4 , Philip J Norris 3 4 9 ; NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-Pediatric (REDS-IV-P)
Affiliations
- PMID: 37250174
- PMCID: PMC10220507
- DOI: 10.1093/ofid/ofad253
Presymptomatic plasma samples from 1596 donors reporting coronavirus disease 2019 infection or symptoms after blood donation were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA and anti-S and anti-N antibodies. Prior infection and vaccination both protected from developing SARS-CoV-2 RNAemia and from symptomatic infection. RNAemia rates did not differ in the Delta and Omicron variant eras.
Keywords: COVID-19; vaccination; viremia.