Biomark Med . Prognostic value of D-dimer/fibrinogen ratio on in-hospital outcomes of patients with heart failure and COVID-19

[tetano]

Biomark Med


. 2021 Oct 20.
doi: 10.2217/bmm-2021-0341. Online ahead of print.
Prognostic value of D-dimer/fibrinogen ratio on in-hospital outcomes of patients with heart failure and COVID-19


Selda Murat ¹ , Bektas Murat ² , Muhammet Dural ¹ , Gurbet Ozge Mert ¹ , Yuksel Cavusoglu ¹



Affiliations

• PMID: 34668382
• DOI: 10.2217/bmm-2021-0341

Abstract

Aim: In the present study, the relationship between D-dimer/fibrinogen ratio (DFR) and in-hospital outcomes was evaluated in patients with COVID-19 and a diagnosis of heart failure (HF). Materials & methods: In-hospital outcomes were compared in patients with high and low DFR values. Results: With regard to in-hospital outcomes, patients in the third tertile of DFR had a higher rate of mechanical ventilation, cardiogenic shock and death (p < 0.001). The length of ICU stay was longer in the third tertile group (p < 0.001). When evaluated together with infection markers, DFR was found to be an independent predictor of outcomes. Conclusion: DFR can be used as a prognostic marker in patients with COVID-19 with a diagnosis of HF, and perhaps more valuable than other infection markers.

Keywords: D-dimer/fibrinogen ratio; coronavirus disease; heart failure.