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J Int Med Res . Chest computed tomography imaging features in patients with coronavirus disease 2019 (COVID-19)

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  • J Int Med Res . Chest computed tomography imaging features in patients with coronavirus disease 2019 (COVID-19)


    J Int Med Res


    . 2021 May;49(5):3000605211010631.
    doi: 10.1177/03000605211010631.
    Chest computed tomography imaging features in patients with coronavirus disease 2019 (COVID-19)


    Hoda Salah Darwish 1 , Mohamed Yasser Habash 2 , Waleed Yasser Habash 3



    Affiliations

    Abstract

    Objective: To analyze computed tomography (CT) features of symptomatic patients with coronavirus disease 2019 (COVID-19).
    Methods: Ninety-five symptomatic patients with COVID-19 confirmed by reverse-transcription polymerase chain reaction from 1 May to 14 July 2020 were retrospectively enrolled. Follow-up CT findings and their distributions were analyzed and compared from symptom onset to late-stage disease.
    Results: Among all patients, 15.8% had unilateral lung disease and 84.2% had bilateral disease with slight right lower lobe predilection (47.4%). Regarding lesion density, 49.4% of patients had pure ground glass opacity (GGO) and 50.5% had GGO with consolidation. Typical early-stage patterns were bilateral lesions in 73.6% of patients, diffuse lesions (41.0%), and GGO (65.2%). Pleural effusion occurred in 13.6% and mediastinal lymphadenopathy in 11.5%. During intermediate-stage disease, 47.4% of patients showed GGO as the disease progressed; however, consolidation was the predominant finding (52.6%).
    Conclusion: COVID-19 pneumonia manifested on lung CT scans with bilateral, peripheral, and right lower lobe predominance and was characterized by diffuse bilateral GGO progressing to or coexisting with consolidation within 1 to 3 weeks. The most frequent CT lesion in the early, intermediate, and late phases was GGO. Consolidation appeared in the intermediate phase and gradually increased, ending with reticular and lung fibrosis-like patterns.

    Keywords: COVID-19; Computed tomography; consolidation; coronavirus; ground glass opacity; viral pneumonia.

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