Respir Investig . The real-time reverse transcription-polymerase chain reaction threshold cycle values for severe acute respiratory syndrome coronavirus 2 predict the prognosis of coronavirus disease 2019 pneumonia

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Respir Investig


. 2021 Jan 28;S2212-5345(21)00008-3.
doi: 10.1016/j.resinv.2020.12.011. Online ahead of print.
The real-time reverse transcription-polymerase chain reaction threshold cycle values for severe acute respiratory syndrome coronavirus 2 predict the prognosis of coronavirus disease 2019 pneumonia


Takahiro Fukushima ¹ , Hiroki Kabata ² , Ryo Yamamoto ¹ , Tomohiro Suhara ¹ , Yoshifumi Uwamino ¹ , Yasushi Kondo ¹ , Katsunori Masaki ¹ , Hirofumi Kamata ¹ , Hiromasa Nagata ¹ , Koichiro Homma ¹ , Yuko Kaneko ¹ , Makoto Ishii ¹ , Junichi Sasaki ¹ , Hiroshi Morisaki ¹ , Naoki Hasegawa ¹ , Koichi Fukunaga ¹ , Keio Donner Project Team



Affiliations

• PMID: 33582075
• DOI: 10.1016/j.resinv.2020.12.011

Abstract

The clinical course of coronavirus disease 2019 (COVID-19) varies from mild to critical. We retrospectively examined whether clinical and laboratory findings on admission could predict COVID-19 prognosis. Among various factors associated with COVID-19 severity, our results indicated that the real-time reverse transcription-polymerase chain reaction (RT-PCR) threshold cycle (Ct) values for severe acute respiratory syndrome coronavirus 2 were the most useful predictor of COVID-19 prognosis.

Keywords: COVID-19; Prognosis; SARS-CoV-2; Severity.