Eur J Clin Microbiol Infect Dis . COVID-19 IgG/IgM antibody testing in Los Angeles County, California

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Eur J Clin Microbiol Infect Dis


. 2020 Nov 25.
doi: 10.1007/s10096-020-04111-3. Online ahead of print.
COVID-19 IgG/IgM antibody testing in Los Angeles County, California


Khadije Ahmad ¹ , Vahid Rezvanizadeh ¹ , Suraj Dahal ¹ , April Kinninger ¹ , Ahmed K Ghanem ¹ , Suvasini Lakshmanan ¹ , Sajad Hamal ¹ , Ferdinand Flores ¹ , Christopher Dailing ¹ , Sion K Roy ¹ , Matthew J Budoff ²



Affiliations

• PMID: 33241444
• DOI: 10.1007/s10096-020-04111-3

Abstract

Evidence suggests that asymptomatic and mild SARS-CoV-2 infections comprise > 95% of all cases. Developing a test that indicates past infection and possible immunity against the virus is important. We administered 244 antibody tests to three groups of high-risk population. The test consisted of an IgG component and an IgM component. The overall IgM/IgG positivity for patients with none, mild, moderate, and severe symptoms were 21.1%, 21.8%, 14.2%, and 26.9%, respectively. Those with moderate or severe symptoms were no more or less likely to have positive antibody tests than those with no or mild symptoms.

Keywords: COVID-19; IgG; IgM; antibodies; coronavirus; testing.