Med Virol . Analysis of the Diagnostic Value of Serum Specific Antibody Testing for Coronavirus Disease 2019

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Med Virol


. 2020 Jun 27.
doi: 10.1002/jmv.26230. Online ahead of print.
Analysis of the Diagnostic Value of Serum Specific Antibody Testing for Coronavirus Disease 2019


Meitian Yan ^{1 2} , Yutong Zheng ^{1 2} , Yanmei Sun ³ , Lan Wang ² , Liang Luan ² , Jing Liu ² , Xiao Tian ² , Nan Wan ²



Affiliations

• PMID: 32592502
• DOI: 10.1002/jmv.26230

Abstract

The coronavirus disease 2019 (COVID-19) pandemic has spread to various regions worldwide. As of 27 April 2020, according to real-time statistics released by the World Health Organization, there have been 84,341 confirmed cases and 4,643 deaths in China, with more than 2,979,484 confirmed cases and 206,450 deaths outside China. The detection of antibodies produced during the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has become an important laboratory method for the diagnosis of COVID-19. However, at present, little research on these specific antibodies has been conducted. In this study, retrospective analysis was used to explore the dynamic changes of serum IgM and IgG antibody and factors affecting diagnostic efficacy, so as to provide a theoretical basis for clinical diagnosis and treatment. This article is protected by copyright. All rights reserved.

Keywords: COVID-19; IgG; IgM; SARS-CoV-2.