Respir Res. The unsynchronized changes of CT image and nucleic acid detection in COVID-19: reports the two cases from Gansu, China

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Respir Res. 2020 Apr 22;21(1):96. doi: 10.1186/s12931-020-01363-7.
The unsynchronized changes of CT image and nucleic acid detection in COVID-19: reports the two cases from Gansu, China.


Gao J^1,2,3, Liu JQ⁴, Wen HJ⁵, Liu H¹, Hu WD¹, Han X⁶, Li CX², Wang XJ⁷.

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Abstract

The novel coronavirus disease (COVID-19) outbreak started in December 2019 in Wuhan, China, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The CT image is used to assess the disease progress, whereas the continued two times of negative results from SARS-CoV-2 nucleic acid detection had been considered as a criterion for ending antiviral treatment. We compared the two COVID-19 cases with similar backgrounds and CT image repeated intervals under treatment. Our report highlighted the unsynchronized expression in the changes of CT image and nucleic acid detection in COVID-19, and lasting positive nucleic acid test result in patients recovered from pneumonia. It may be contributed to recognize the disease and improve prevention.



KEYWORDS:

COVID-19; CT image; Nucleic acid detection; SARS-CoV-2


PMID:32321530DOI:10.1186/s12931-020-01363-7