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Flu Super Strains Could Emerge Decades After Their Disappearance
Influenza super-strains can emerge through recombination of strains from birds, pigs, and humans. However, once a new recombinant strain emerges, it is not clear whether the strain is capable of sustaining an outbreak. In certain cases, such strains have caused major influenza pandemics. Brian J. Coburn, of the Center for Biomedical Modeling at the David Geffen School of Medicine, University of California, Los Angeles, and colleagues, developed a multi-host (i.e., birds, pigs, and humans) and multi-strain model of influenza to analyze the outcome of emergent strains. In the model, pigs acted as "mixing vessels" for avian and human strains and can produce super-strains from genetic recombination...
...Reference: Coburn BJ, Cosner C and Ruan S. Emergence and dynamics of influenza super-strains. BMC Public Health 2011, 11 (Suppl 1):S6doi:10.1186/1471-2458-11-S1-S6
Flu Super Strains Could Emerge Decades After Their Disappearance
Influenza super-strains can emerge through recombination of strains from birds, pigs, and humans. However, once a new recombinant strain emerges, it is not clear whether the strain is capable of sustaining an outbreak. In certain cases, such strains have caused major influenza pandemics. Brian J. Coburn, of the Center for Biomedical Modeling at the David Geffen School of Medicine, University of California, Los Angeles, and colleagues, developed a multi-host (i.e., birds, pigs, and humans) and multi-strain model of influenza to analyze the outcome of emergent strains. In the model, pigs acted as "mixing vessels" for avian and human strains and can produce super-strains from genetic recombination...
...Reference: Coburn BJ, Cosner C and Ruan S. Emergence and dynamics of influenza super-strains. BMC Public Health 2011, 11 (Suppl 1):S6doi:10.1186/1471-2458-11-S1-S6