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Influenza induced lung Trm: Not all memories last forever

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  • Influenza induced lung Trm: Not all memories last forever

    Immunol Cell Biol. 2017 Apr 13. doi: 10.1038/icb.2017.32. [Epub ahead of print]
    Influenza induced lung Trm: Not all memories last forever.

    Van Braeckel-Budimir N1, Harty JT1,2,3.
    Author information

    Abstract

    In the light of new findings that lung tissue resident memory CD8+ T cells (Trm) represent major mediators of heterosubtypic immunity against influenza virus, it is of utmost importance to understand the basic biological mechanisms behind induction, formation and maintenance of this cell population. Addressing these important knowledge gaps will potentially inform development of superior, broadly-protective influenza vaccines and new immunization strategies.Immunology and Cell Biology accepted article preview online, 13 April 2017. doi:10.1038/icb.2017.32.


    PMID: 28405016 DOI: 10.1038/icb.2017.32
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