Preprint for Journal of Infection: Prior SARS-CoV-2 infection is associated with protection against symptomatic reinfection

[sharon sanders]

Prior SARS-CoV-2 infection is associated with protection against symptomatic reinfection

Aidan T. Hanrath MBBS , Brendan A.I. Payne PhD , Christopher J.A. Duncan DPhil , The NUTH HCW Testing Group, Ina Schim van der Loeff , Kenneth F. Baker , David A. Price , Peter McDowall , Kiera McDowall , Sue Cook , Peter Towns , Ulrich Schwab , Adam Evans , Jill Dixon , Jennifer Collins , Shirelle Burton-Fanning , David Saunders , Jayne Harwood , Julie Samuel , Matthias L. Schmid , Lucia Pareja-Cebrian , Ewan Hunter , Yusri Taha , Elizabeth Murphy PII: S0163-4453(20)30781-7 DOI: https://doi.org/10.1016/j.jinf.2020.12.023 Reference: YJINF 4976

To appear in: Journal of Infection Accepted date: 23 December 2020

Highlights

 Whether SARS-CoV-2 infection confers immunity to reinfection is uncertain

 The ‘second wave’ of transmission offered an opportunity to examine this

 We observed no symptomatic reinfections in a cohort of healthcare workers

 This apparent immunity to re-infection was maintained for at least 6 months

 Further studies are required to define immunological mechanism(s) and durability

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https://www.journalofinfection.com/action/showPdf?pii=S0163-4453%2820%2930781-7