Update on Avian Influenza A (H5N1) Virus Infection in Humans
Writing Committee of the Second World Health Organization Consultation on Clinical Aspects of Human Infection with Avian Influenza A (H5N1) Virus
The New England Journal of Medicine, Volume 358:261-273 January 17, 2008 Number 3

The unprecedented epizootic of avian influenza A (H5N1) viruses among birds continues to cause human disease with high mortality and to pose the threat of a pandemic. This review updates a 2005 report1 and incorporates information recently published or presented at the Second World Health Organization (WHO) Consultation on Clinical Aspects of Human Infection with Avian Influenza A (H5N1) Virus. . . .
Full text and figures available from NEJM for free at: http://content.nejm.org/cgi/content/full/358/3/261

Figure 1. Evolution of the Hemagglutinin and Other Key Mutations Associated with Virulence or Drug Resistance in Avian Influenza A (H5N1) Virus.
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