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Hum Vaccin Immunother. 2012 Jan 1;8(1). [Epub ahead of print]
Influenza viruses: From birds to humans.
Reperant LA, Kuiken T, Osterhaus AD.
Source
Department of Virology, Erasmus MC; Rotterdam, the Netherlands.
Abstract
Avian influenza viruses are the precursors of human influenza A viruses. They may be transmitted directly from avian reservoirs, or infect other mammalian species before subsequent transmission to their human host. So far, avian influenza viruses have caused sporadic-yet increasingly more frequently recognized-cases of infection in humans. They have to adapt to and circulate efficiently in human populations, before they may trigger a worldwide human influenza outbreak or pandemic. Cross-species transmission of avian influenza viruses from their reservoir hosts-wild waterbirds-to terrestrial poultry and to humans is based on different modes of transmission and results in distinctive pathogenetic manifestations, which are reviewed in this paper.
PMID:
22251997
[PubMed - as supplied by publisher]
Influenza viruses: From birds to humans.
Reperant LA, Kuiken T, Osterhaus AD.
Source
Department of Virology, Erasmus MC; Rotterdam, the Netherlands.
Abstract
Avian influenza viruses are the precursors of human influenza A viruses. They may be transmitted directly from avian reservoirs, or infect other mammalian species before subsequent transmission to their human host. So far, avian influenza viruses have caused sporadic-yet increasingly more frequently recognized-cases of infection in humans. They have to adapt to and circulate efficiently in human populations, before they may trigger a worldwide human influenza outbreak or pandemic. Cross-species transmission of avian influenza viruses from their reservoir hosts-wild waterbirds-to terrestrial poultry and to humans is based on different modes of transmission and results in distinctive pathogenetic manifestations, which are reviewed in this paper.
PMID:
22251997
[PubMed - as supplied by publisher]
