An avian influenza virus A(H7N9) reassortant that recently emerged in the United States with low pathogenic phenotype does not efficiently infect swine

[tetano]

Influenza Other Respir Viruses. 2019 Feb 13. doi: 10.1111/irv.12631. [Epub ahead of print]
An avian influenza virus A(H7N9) reassortant that recently emerged in the United States with low pathogenic phenotype does not efficiently infect swine.

Powell JD¹, Abente EJ¹, Torchetti MK², Killian ML², Vincent AL¹.
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Abstract

In 2017, outbreaks of low and highly pathogenic avian H7N9 viruses were reported in four States in the United States. In total, over 270 000 birds died or were culled, causing significant economic loss. The potential for avian-to-swine transmission of the U.S. avian H7N9 was unknown. In an experimental challenge in swine using a representative low pathogenic H7N9 (A/chicken/Tennessee/17-007431-3/2017; LPAI TN/17) isolated from these events, no infectious virus in the upper and minimal virus in the lower respiratory tract was detected, nor was lung pathology or evidence of transmission in pigs observed, indicating that the virus cannot efficiently infect swine.
? 2019 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.


KEYWORDS:

LPAI ; H7N9; avian influenza; influenza; swine

PMID: 30761746 DOI: 10.1111/irv.12631
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