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Clin Respir J. ARDS associated with pneumonia caused by avian influenza A H7N9 virus treated with extracorporeal membrane oxygenation.

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  • Clin Respir J. ARDS associated with pneumonia caused by avian influenza A H7N9 virus treated with extracorporeal membrane oxygenation.

    [Source: US National Library of Medicine, full page: (LINK). Abstract, edited.]


    Clin Respir J. 2014 Apr 14. doi: 10.1111/crj.12140. [Epub ahead of print]

    ARDS associated with pneumonia caused by avian influenza A H7N9 virus treated with extracorporeal membrane oxygenation.

    Tang X<SUP>1</SUP>, He H, Sun B, Wan J, Ban C, Zhang C, Wang S, Xia J, Li J, Liu Y, Cao B, Tong Z.

    Author information: <SUP>1</SUP>Department of Respiratory and Critical Care Medicine, Beijing Chao-Yang Hospital, Beijing Institute of Respiratory Medicine, Capital Medical University, Beijing, China.


    Abstract

    This is a sporadic H7N9 avian influenza case that was the first severe imported case in Beijing and the first case of Hebei province in China. A 61-year old female who had rapidly progressive pneumonia with respiratory distress and bilateral exduation and consolidation changes on chest X-ray and CT scan that did not respond to ordinary antibiotics was diagnosed with influenza A (H7N9) infection in our hospital On July 19<SUP>th</SUP> 2013. Intravenous peramivir, VV-ECMO and CVVH were given on the same day of lab-diagnosis because of severe ARDS and acute renal failure. With antimicrobial therapy and other supportive treatment, clinical symptoms and oxygenation of the patient improved gradually. VV-ECMO was successfully removed on the 13th day. The testing for influenza A (H7N9) turned negative on day 16 since the antivirus therapy. 23 days after hospitalization, blood stream infection with multi-drug resistant Acinetobacter Baumannii occurred which lead to septic shock and death. Whether or not the influenza season in north China, the influenza screening should be carried out as a conventional test for the patients who are suspected of viral pneumonia. For the patients who need mechanical ventilation and ECMO support, the lung protective strategy under the guidance of transpulmonary pressure may be helpful for recovering the lung.

    This article is protected by copyright. All rights reserved.

    KEYWORDS: H7N9 avian influenza pneumonia, extracorporeal membrane oxygenation, multi-drug resistant Acinetobacter Baumannii, nosocomial infections


    PMID: 24725670 [PubMed - as supplied by publisher]


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