Originally posted by AnnaLisa
View Post
Announcement
Collapse
No announcement yet.
Effects of oseltamivir phosphate (Tamiflu) in human sera on results of microneutralization and hemagglutinin-inhibition tests for H5N2 avian influenza virus
Collapse
X
-
-
Thank you Emily. Looks like they will have to use PCR testing on humans.
Leave a comment:
-
Effects of oseltamivir phosphate (Tamiflu) in human sera on results of microneutralization and hemagglutinin-inhibition tests for H5N2 avian influenza virus
Arch Virol. 2008;153(5):945-9. doi: 10.1007/s00705-008-0038-5. Epub 2008 Jan 29.
Effects of oseltamivir phosphate (Tamiflu) in human sera on results of microneutralization and hemagglutinin-inhibition tests for H5N2 avian influenza virus.
Yamazaki Y1, Doy M, Yamato S, Kawada Y, Ogata T.
Author information
Abstract
To determine the influence of oseltamivir phosphate (Tamiflu) on the results of microneutralization and hemagglutinin-inhibition (HI) tests in human sera with H5N2 influenza virus, ten volunteers were administered Tamiflu and blood samples were collected. In the microneutralization test, no consistent effects were observed. However, in the HI test, specimens from all volunteers taken at 4 and 7 h after drug administration showed a higher titer as compared to 0 and 24 h after administration when mammalian cells (horse, guinea pig, and human) were used. These results suggest that the administration of Tamiflu may affect the results of HI tests for H5N2 virus.
PMID: 18227965 [PubMed - indexed for MEDLINE]
Leave a comment: