Elife. 2013 May 14;2:e00842. doi: 10.7554/eLife.00842. Print 2013.
Influenza evolution navigates stability valleys.
Rorick MM, Pascual M.
Source
is at the Department of Ecology and Evolutionary Biology , University of Michigan , Ann Arbor , United States rorick@umich.edu.
Abstract
By reconstructing how an influenza protein collected in 1968 might have evolved into one collected in 2007, researchers have obtained new insights into the interactions between genetic mutations.
KEYWORDS:
Viruses, epistasis, influenza, protein evolution, protein instability
PMID:
23682318
[PubMed]
PMCID:
PMC3654458
Free PMC Article
Influenza evolution navigates stability valleys.
Rorick MM, Pascual M.
Source
is at the Department of Ecology and Evolutionary Biology , University of Michigan , Ann Arbor , United States rorick@umich.edu.
Abstract
By reconstructing how an influenza protein collected in 1968 might have evolved into one collected in 2007, researchers have obtained new insights into the interactions between genetic mutations.
KEYWORDS:
Viruses, epistasis, influenza, protein evolution, protein instability
PMID:
23682318
[PubMed]
PMCID:
PMC3654458
Free PMC Article