Infect Control Hosp Epidemiol . Linking sporadic hospital clusters during a community surge of the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) B.1.617.2 delta variant: The utility of whole-genome sequencing

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Infect Control Hosp Epidemiol


. 2022 Apr 27;1-5.
doi: 10.1017/ice.2022.106. Online ahead of print.
Linking sporadic hospital clusters during a community surge of the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) B.1.617.2 delta variant: The utility of whole-genome sequencing


Liang En Wee ^{1 2} , Karrie Kwan-Ki Ko ^{3 4 5 2} , Edwin Philip Conceicao ⁶ , Jean Xiang-Ying Sim ^{1 6} , Nurdyana Abdul Rahman ^{4 2} , Shireen Yan-Ling Tan ^{4 2} , Delphine Yan-Hong Cao ⁴ , Kenneth Xing-Long Chan ³ , May Kyawt Aung ⁶ , Myat Oo Aung ⁶ , Yang Yong ⁶ , Shalvi Arora ⁶ , Molly Kue Bien How ⁶ , Kwee Yuen Tan ⁶ , Lai Chee Lee ⁶ , Thuan Tong Tan ¹ , Limin Wijaya ¹ , James Heng Chiak Sim ⁴ , Chayaporn Suphavilai ⁵ , Indumathi Venkatachalam ^{1 6} , Moi Lin Ling ⁶



Affiliations

• PMID: 35473629
• DOI: 10.1017/ice.2022.106

Abstract

Sporadic clusters of healthcare-associated coronavirus disease 2019 (COVID-19) occurred despite intense rostered routine surveillance and a highly vaccinated healthcare worker (HCW) population, during a community surge of the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) B.1.617.2 δ (delta) variant. Genomic analysis facilitated timely cluster detection and uncovered additional linkages via HCWs moving between clinical areas and among HCWs sharing a common lunch area, enabling early intervention.