Front Microbiol
. 2020 Jun 5;11:1316.
doi: 10.3389/fmicb.2020.01316. eCollection 2020.
SARS-CoV-2 Genome Analysis of Japanese Travelers in Nile River Cruise
Tsuyoshi Sekizuka 1 , Sanae Kuramoto 2 , Eri Nariai 2 , Masakatsu Taira 3 , Yushi Hachisu 3 , Akihiko Tokaji 4 , Michiyo Shinohara 5 , Tsuyoshi Kishimoto 5 , Kentaro Itokawa 1 , Yusuke Kobayashi 6 , Keisuke Kadokura 6 , Hajime Kamiya 6 , Tamano Matsui 6 , Motoi Suzuki 6 , Makoto Kuroda 1
Affiliations
- PMID: 32582136
- PMCID: PMC7291780
- DOI: 10.3389/fmicb.2020.01316
Abstract
Japan has reported 26 cases of coronavirus disease 2019 (COVID-19) linked to cruise tours on the River Nile in Egypt between March 5 and 15, 2020. Here, we characterized the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome of isolates from 10 travelers who returned from Egypt and from patients possibly associated with these travelers. We performed haplotype network analysis of SARS-CoV-2 isolates using genome-wide single-nucleotide variations. Our analysis identified two potential Egypt-related clusters from these imported cases, and these clusters were related to globally detected viruses in different countries.
Keywords: cruise ship; genome epidemiology; haplotype network; imported case; single-nucleotide variations.