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Influenza B false-positive results by rapid molecular tests Alere™ i Influenza A&B 2 in France

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  • Influenza B false-positive results by rapid molecular tests Alere™ i Influenza A&B 2 in France

    Diagn Microbiol Infect Dis. 2019 Mar 13. pii: S0732-8893(19)30094-X. doi: 10.1016/j.diagmicrobio.2019.03.002. [Epub ahead of print]
    Influenza B false-positive results by rapid molecular tests Alere™ i Influenza A&B 2 in France.

    Otto MP1, Toyer AL2, Poggi C2, Janvier F3.
    Author information

    Abstract

    The Alere-i™ Influenza A&B (Abbott), a nicking endonuclease amplification reaction test, has recently been improved in order to deliver results in a few minutes. Our field observation highlights two problems with this new version: improper interpretation of a test as valid despite improper reagent hydration and falsely influenza B positive results. We advise users of the new system to check reagent hydration prior to reporting a result and to systematically confirm positive influenza B results.
    Copyright © 2019 Elsevier Inc. All rights reserved.


    KEYWORDS:

    Alere i a/B 2; False positive; Influenza; Rapid molecular tests

    PMID: 30971360 DOI: 10.1016/j.diagmicrobio.2019.03.002
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