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Detection Methods of Human and Animal Influenza Virus-Current Trends

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  • Detection Methods of Human and Animal Influenza Virus-Current Trends

    Biosensors (Basel). 2018 Oct 18;8(4). pii: E94. doi: 10.3390/bios8040094.
    Detection Methods of Human and Animal Influenza Virus-Current Trends.

    Dziąbowska K1,2, Czaczyk E3,4, Nidzworski D5,6.
    Author information

    Abstract

    The basic affairs connected to the influenza virus were reviewed in the article, highlighting the newest trends in its diagnostic methods. Awareness of the threat of influenza arises from its ability to spread and cause a pandemic. The undiagnosed and untreated viral infection can have a fatal effect on humans. Thus, the early detection seems pivotal for an accurate treatment, when vaccines and other contemporary prevention methods are not faultless. Public health is being attacked with influenza containing new genes from a genetic assortment between animals and humankind. Unfortunately, the population does not have immunity for mutant genes and is attacked in every viral outbreak season. For these reasons, fast and accurate devices are in high demand. As currently used methods like Rapid Influenza Diagnostic Tests lack specificity, time and cost-savings, new methods are being developed. In the article, various novel detection methods, such as electrical and optical were compared. Different viral elements used as detection targets and analysis parameters, such as sensitivity and specificity, were presented and discussed.


    KEYWORDS:

    ELISA; PCR; Rapid Influenza Diagnostic Tests RIDTs; electrochemical detection; influenza virus; optical detection

    PMID: 30340339 DOI: 10.3390/bios8040094
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