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Detection of influenza A, B and subtypes A (H1N1) pdm09, A (H3N2) viruses by multiple qrt-pcr in clinical samples

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  • Detection of influenza A, B and subtypes A (H1N1) pdm09, A (H3N2) viruses by multiple qrt-pcr in clinical samples

    Rev Peru Med Exp Salud Publica. 2017 Apr-Jun;34(2):192-200. doi: 10.17843/rpmesp.2017.342.2054.
    [Detection of influenza A, B and subtypes A (H1N1) pdm09, A (H3N2) viruses by multiple qrt-pcr in clinical samples].

    [Article in Spanish; Abstract available in Spanish from the publisher]
    Marcos P1, Huaringa M1, Rojas N1, Guti?rrez V1, Ruiton S1, Gallardo E1, Achata J1, Galarza M2.
    Author information

    Abstract

    in English, Spanish
    OBJECTIVES.:

    To describe the clinical and epidemiological characteristics of patients diagnosed with epidermolysis bullosa (EB) at the Instituto Nacional de Salud (INSN) in Lima, Peru; a National Reference Center for this disease.
    MATERIAL AND METHODS:

    . Observational, descriptive and transversal study. We reviewed the clinical histories and laboratory tests of patients diagnosed with EB treated in INSN from 1993 to 2015.
    RESULTS.:

    93 patients were registered. The average age was 7.9 ? 5.6 years; 53.8% (n = 50) were boys. Clinical forms corresponded to dystrophic EB with 41 (44.1%) cases, simple EB with 39 (41.9%) union EB cases with 8 (8.6%) and Kindler syndrome with 4 (4.3%) cases. The clinical form could not be identified in a case. A total of 48 cases (51.6%) came from Lima and Callao, and 45 cases (48.4%) from other provinces of the country. Extracutaneous manifestations involved gastrointestinal (44.1%), ocular (37.6%), odontogenic (87.1%), and nutritional (79.6%) involvement, as well as pseudosindactilia (16.1%). Chronic malnutrition (71.6%), acute malnutrition (17.6%) and anemia (62.4%) were found. Mortality corresponded to 6 cases (6.5%).
    CONCLUSIONS.:

    93 cases of EB were reported in INSN, the predominant clinical presentation was the dystrophic form.


    PMID: 29177376 DOI: 10.17843/rpmesp.2017.342.2054
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