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Reactivity and sensitivity of commercially available influenza rapid diagnostic tests in Japan

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  • Reactivity and sensitivity of commercially available influenza rapid diagnostic tests in Japan

    Sci Rep. 2017 Nov 3;7(1):14483. doi: 10.1038/s41598-017-14536-0.
    Reactivity and sensitivity of commercially available influenza rapid diagnostic tests in Japan.

    Sakai-Tagawa Y1, Yamayoshi S1, Kawakami C2, Le MQ3, Uchida Y4, Saito T4, Nidom CA5, Humaira I6, Toohey-Kurth K7, Arafa AS8, Liu MT9, Shu Y10, Kawaoka Y11,12,13,14.
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    Abstract

    Seasonal influenza virus routinely causes epidemic infections throughout the world. Sporadic infections by H5N1, H5N6, and H7N9 viruses are also reported. To treat patients suffering from such viral infections, broadly reactive and highly sensitive influenza rapid diagnostic tests (IRDTs) are required. Here, we examined the reactivity and sensitivity of 25 IRDTs available in Japan for the detection of seasonal H1N1pdm09, H3N2, and type B viruses, as well as highly pathogenic H5 and H7 viruses. All of the IRDTs tested detected the seasonal viruses and H5 and H7 viruses albeit with different sensitivities. Several IRDTs detected the H5 and H7 viruses and the seasonal viruses with similar (high) sensitivity.


    PMID: 29101372 DOI: 10.1038/s41598-017-14536-0
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