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Pediatr Int. 2017 Sep 22. doi: 10.1111/ped.13428. [Epub ahead of print]
Changes in Trends and Impact of Testing for Influenza in Infants with Fever under 90 Days of Age.
Kim S1,2, Moon HM1,2, Lee JK1, Rhie K1, Yoon KW1,2, Choi EH1,3, Lee HJ1,3, Lee H2,3.
Author information
Abstract
BACKGROUND:
Infants less than 90 days who present with fever are commonly subject to various invasive procedures due to risk of bacterial infections in this age group. However a great proportion are due to viral infections, including influenza. The aim of this study was to assess the impact of testing influenza in infants < 90 days with fever as well as analyze the subjects' characteristics to identify which infants should be considered for such testing.
METHODS:
Clinical characteristics and trends in influenza virus testing and treatment were analyzed among febrile infants <90 days who came to the emergency room and were diagnosed with influenza during 2005 to 2015.
RESULTS:
Among 5,347 febrile infants <90 days, 963 (18%) underwent influenza viral study. A total of 114 (11.8%) infants were diagnosed with influenza. The positive rates were up to 67% of the febrile infants during the epidemics. Among them, 83 had a history of family contact. While more than half presented with upper respiratory symptoms, 34% showed only fever without respiratory symptoms. A decrease in antibiotic use and admission rates during the study period among infants diagnosed with influenza was seen (p for trend <0.05).
CONCLUSIONS:
During the influenza epidemic season, diagnostic tests for influenza based on a detailed contact history are necessary in assessing the cause of fever. Targeted testing for influenza may lead to a decrease in antibiotic use and admission rates in young infants. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
Fever; Infant; Influenza
PMID: 28940983 DOI: 10.1111/ped.13428
Changes in Trends and Impact of Testing for Influenza in Infants with Fever under 90 Days of Age.
Kim S1,2, Moon HM1,2, Lee JK1, Rhie K1, Yoon KW1,2, Choi EH1,3, Lee HJ1,3, Lee H2,3.
Author information
Abstract
BACKGROUND:
Infants less than 90 days who present with fever are commonly subject to various invasive procedures due to risk of bacterial infections in this age group. However a great proportion are due to viral infections, including influenza. The aim of this study was to assess the impact of testing influenza in infants < 90 days with fever as well as analyze the subjects' characteristics to identify which infants should be considered for such testing.
METHODS:
Clinical characteristics and trends in influenza virus testing and treatment were analyzed among febrile infants <90 days who came to the emergency room and were diagnosed with influenza during 2005 to 2015.
RESULTS:
Among 5,347 febrile infants <90 days, 963 (18%) underwent influenza viral study. A total of 114 (11.8%) infants were diagnosed with influenza. The positive rates were up to 67% of the febrile infants during the epidemics. Among them, 83 had a history of family contact. While more than half presented with upper respiratory symptoms, 34% showed only fever without respiratory symptoms. A decrease in antibiotic use and admission rates during the study period among infants diagnosed with influenza was seen (p for trend <0.05).
CONCLUSIONS:
During the influenza epidemic season, diagnostic tests for influenza based on a detailed contact history are necessary in assessing the cause of fever. Targeted testing for influenza may lead to a decrease in antibiotic use and admission rates in young infants. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
KEYWORDS:
Fever; Infant; Influenza
PMID: 28940983 DOI: 10.1111/ped.13428