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Comparison of influenza and RSV diagnostic from nasopharyngeal swabs by rapid fluorescent immunoassay (Sofia system) and rapid bedside testing (BinaxNOW) vs. conventional fluorescent immunoassay in a German university children's hospital

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  • Comparison of influenza and RSV diagnostic from nasopharyngeal swabs by rapid fluorescent immunoassay (Sofia system) and rapid bedside testing (BinaxNOW) vs. conventional fluorescent immunoassay in a German university children's hospital

    Infection. 2017 Mar 13. doi: 10.1007/s15010-017-1001-8. [Epub ahead of print]
    Comparison of influenza and RSV diagnostic from nasopharyngeal swabs by rapid fluorescent immunoassay (Sofia system) and rapid bedside testing (BinaxNOW) vs. conventional fluorescent immunoassay in a German university children's hospital.

    Rack-Hoch AL1, Laniado G2, H?bner J2.
    Author information

    Abstract

    The Sofia fluorescent immunoassay showed excellent sensitivity and specificity compared to conventional fluorescent immunoassay for Influenza A (Influenza B was not detected during the study period) and RSV in patients with suspected ILI (influenza-like illness). Thus the fast and easy-to-handle Sofia FIA leads to rapid and reliable diagnosis, which can be used by clinicians to avoid unnecessary antibiotic treatment and rapidly identify patients who need to be isolated upon hospital admission.


    KEYWORDS:

    Child; Influenza; Nasopharyngeal swab; RSV; Rapid fluorescent immunoassay

    PMID: 28290129 DOI: 10.1007/s15010-017-1001-8

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