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Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients

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  • Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients

    Open Forum Infect Dis. 2016 Mar 8;3(1):ofw023. doi: 10.1093/ofid/ofw023. eCollection 2016.
    Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients.

    Reddy KP1, Bajwa EK2, Parker RA3, Onderdonk AB4, Walensky RP5.
    Author information

    Abstract

    Among critically ill patients with lower respiratory tract (LRT)-confirmed influenza, we retrospectively observed worse 28-day clinical outcomes in upper respiratory tract (URT)-negative versus URT-positive subjects. This finding may reflect disease progression and highlights the need for influenza testing of both URT and LRT specimens to improve diagnostic yield and possibly inform prognosis.


    KEYWORDS:

    critically ill; influenza diagnosis; lower respiratory tract; upper respiratory tract

    PMID: 26966696 [PubMed] PMCID: PMC4784015 Free PMC Article
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