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A Highly Sensitive Europium Nanoparticle Immunoassay for Detection of Influenza A/B Virus Antigen in Clinical Specimens

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  • A Highly Sensitive Europium Nanoparticle Immunoassay for Detection of Influenza A/B Virus Antigen in Clinical Specimens

    J Clin Microbiol. 2014 Oct 8. pii: JCM.02635-14. [Epub ahead of print]
    A Highly Sensitive Europium Nanoparticle Immunoassay for Detection of Influenza A/B Virus Antigen in Clinical Specimens.
    Zhang P1, Vemula SV2, Zhao J1, Du B1, Mohan H1, Liu J1, Sittana H3, Mubarak E4, Landry ML5, Hewlett I6.
    Author information
    Abstract

    We report the development of a novel europium nanoparticle-based immunoassay (ENIA) for rapid detection of influenza A and influenza B viruses. ENIA demonstrated a sensitivity of 90.7% (147/162) for influenza A viruses and 81.80 % (9/11) for influenza B viruses compared to a in house RT-PCR assay while testing influenza-positive clinical samples.

    Copyright ? 2014, American Society for Microbiology. All Rights Reserved.

    PMID:
    25297327
    [PubMed - as supplied by publisher]

    We report the development of a novel europium nanoparticle-based immunoassay (ENIA) for rapid detection of influenza A and influenza B viruses. The ENIA demonstrated sensitivities of 90.7% (147/162) for influenza A viruses and 81.80% (9/11) for influenza B viruses compared to those for an in-house r …
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