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Comparative evaluation of the Nanosphere Verigene RV+ Assay with the Simplexa Flu A/B & RSV Kit for the detection of influenza and respiratory syncytial viruses

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  • Comparative evaluation of the Nanosphere Verigene RV+ Assay with the Simplexa Flu A/B & RSV Kit for the detection of influenza and respiratory syncytial viruses

    J Clin Microbiol. 2012 Nov 14. [Epub ahead of print]
    Comparative evaluation of the Nanosphere Verigene RV+ Assay with the Simplexa Flu A/B & RSV Kit for the detection of influenza and respiratory syncytial viruses.
    Alby K, Popowitch EB, Miller MB.
    Source

    Clinical Microbiology/Immunology Laboratories UNC Health Care, Chapel Hill, NC.
    Abstract

    Using retrospective (n=200) and prospective (n=150) nasopharyngeal specimens, we evaluated the Nanosphere Verigene RV+ and the Focus Diagnostics Simplexa Flu A/B & RSV tests. Overall, the RV+ demonstrated a sensitivity/specificity of 96.6%/100% for influenza A, 100%/99.7% for influenza B, and 100%/100% for RSV, while the Simplexa test sensitivity/specificity was 82.8%/99.7%, 76.2%/100% and 94.6%/100%, respectively.

    PMID:
    23152547
    [PubMed - as supplied by publisher]

    Using retrospective (n = 200) and prospective (n = 150) nasopharyngeal specimens, we evaluated the Nanosphere Verigene RV+ and the Focus Diagnostics Simplexa Flu A/B & RSV tests. Overall, RV+ demonstrated sensitivities and specificities of 96.6% and 100% for influenza A virus, 100% and 99.7% for …
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