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Volume 28, Number 8—August 2022
DOI: 10.3201/eid2808.212530
Min Gu1, Kaibiao Chen1, Zhichuang Ge, Jun Jiao, Tianyu Cai, Suhan Liu, Xiaoquan Wang, Xinan Jiao, Daxin Peng, and Xiufan Liu
Abstract
We investigated genetic and biologic characteristics of 2 Eurasian avian-like H1N1 swine influenza viruses from pigs in China that belong to the predominant G4 genotype. One swine isolate exhibited strikingly great homology to contemporaneous human Eurasian avian-like H1N1 isolates, preferential binding to the human-type receptor, and vigorous replication in mice without adaptation.
DOI: 10.3201/eid2808.212530
Min Gu1, Kaibiao Chen1, Zhichuang Ge, Jun Jiao, Tianyu Cai, Suhan Liu, Xiaoquan Wang, Xinan Jiao, Daxin Peng, and Xiufan Liu
Abstract
We investigated genetic and biologic characteristics of 2 Eurasian avian-like H1N1 swine influenza viruses from pigs in China that belong to the predominant G4 genotype. One swine isolate exhibited strikingly great homology to contemporaneous human Eurasian avian-like H1N1 isolates, preferential binding to the human-type receptor, and vigorous replication in mice without adaptation.