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J Assoc Physicians India. 2019 Apr;67(4):37-41.
Imaging Spectrum of H1N1 Influenza from a Tertiary Liver Hospital in India: First Ever Experience.
Laroia ST1, Gupta E2, Kumar S3, Kumar G4, Sarin SK5.
Author information
Abstract
Context:
To review the imaging spectrum, clinical profile and disease outcome of patients with H1N1 influenza at a tertiary liver hospital.
Aim:
To review the imaging spectrum, clinical profile and disease outcome of patients with H1N1 influenza at a tertiary liver hospital.
Settings and Design:
A retrospective analysis of imaging findings of 21 patients with H1N1 flu, admitted to our hospital from September 2014-March 2015, was done.
Methods and Material:
All patients with H1N1 virus infection were included. Mode of hospital admission, concomitant liver disease, clinical findings, liver function tests and viral markers for hepatitis B and C infections were studied. Chest imaging findings on CXR or HRCT were analyzed. Correlation with CLD, clinical course, mortality and morbidity was reviewed.
Statistical Analysis Used:
Analysis was performed with SPSS version. Mean ? standard deviation (SD), number and percentage, chi-square or Fisher exact test, t-test and odds ratio were calculated as appropriate.
Results:
The mean age was 43.52 ? 14.2 years (18 males, 3 females). Positive CXR and HRCT findings were found in 14/21 (66.7%) and 19/21 (90.5%) respectively. Commonest abnormalities observed were bilateral consolidation and ground glass opacities (9/21, 42.9% each). Mid zone distribution was seen in 15/21(71.4%). Underlying CLD was seen in 14/21 (66.7%) with positive findings in 11/14 (78.6%) on CXR and 13/14 (92.9%) on HRCT. Presence of pleural effusion (PE)(57.1%) and lymphadenopathy(50%) were statistically significant (p<0.05). Median length of hospital stay was longer: 12 days (IQR 1-30) with significant mortality rate in this group.
Conclusions:
Imaging profile of patients with H1N1 influenza revealed that patients with underlying CLD were more likely to have imaging findings, pleural effusion, lymphadenopathy, receive intensive care and longer hospital stay with increased risk for mortality.
? Journal of the Association of Physicians of India 2011.
PMID: 31311217
Imaging Spectrum of H1N1 Influenza from a Tertiary Liver Hospital in India: First Ever Experience.
Laroia ST1, Gupta E2, Kumar S3, Kumar G4, Sarin SK5.
Author information
Abstract
Context:
To review the imaging spectrum, clinical profile and disease outcome of patients with H1N1 influenza at a tertiary liver hospital.
Aim:
To review the imaging spectrum, clinical profile and disease outcome of patients with H1N1 influenza at a tertiary liver hospital.
Settings and Design:
A retrospective analysis of imaging findings of 21 patients with H1N1 flu, admitted to our hospital from September 2014-March 2015, was done.
Methods and Material:
All patients with H1N1 virus infection were included. Mode of hospital admission, concomitant liver disease, clinical findings, liver function tests and viral markers for hepatitis B and C infections were studied. Chest imaging findings on CXR or HRCT were analyzed. Correlation with CLD, clinical course, mortality and morbidity was reviewed.
Statistical Analysis Used:
Analysis was performed with SPSS version. Mean ? standard deviation (SD), number and percentage, chi-square or Fisher exact test, t-test and odds ratio were calculated as appropriate.
Results:
The mean age was 43.52 ? 14.2 years (18 males, 3 females). Positive CXR and HRCT findings were found in 14/21 (66.7%) and 19/21 (90.5%) respectively. Commonest abnormalities observed were bilateral consolidation and ground glass opacities (9/21, 42.9% each). Mid zone distribution was seen in 15/21(71.4%). Underlying CLD was seen in 14/21 (66.7%) with positive findings in 11/14 (78.6%) on CXR and 13/14 (92.9%) on HRCT. Presence of pleural effusion (PE)(57.1%) and lymphadenopathy(50%) were statistically significant (p<0.05). Median length of hospital stay was longer: 12 days (IQR 1-30) with significant mortality rate in this group.
Conclusions:
Imaging profile of patients with H1N1 influenza revealed that patients with underlying CLD were more likely to have imaging findings, pleural effusion, lymphadenopathy, receive intensive care and longer hospital stay with increased risk for mortality.
? Journal of the Association of Physicians of India 2011.
PMID: 31311217