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Clin Exp Nephrol. 2011 Nov 25. [Epub ahead of print]
Relapse of minimal change disease following infection with the 2009 pandemic influenza (H1N1) virus.
Kim SR, Lee SB, Kim IY, Lee DW, Rhee H, Seong EY, Song SH, Kwak IS.
Source
Division of Nephrology, Department of Internal Medicine, Pusan National University School of Medicine, Beomeo-ri, Mulgeum-eup, Yangsan, Gyeongsangnam-do, 626-770, South Korea.
Abstract
We report a case of relapse of minimal change disease following infection with the influenza A (H1N1) virus responsible for the 2009 pandemic. A 22-year-old man who had been diagnosed with minimal change disease presented with systemic edema. He had achieved complete remission with an oral steroid (prednisolone 1 mg/kg/day) by the 17th day of administration. On the 27th day of prednisolone administration, he presented with a new onset of generalized edema after several days of productive coughing. His urine showed proteinuria (4+) with a protein/creatinine ratio (PCR) of 2852.1 mg/g. His nasal swab sample was positive for the 2009 pandemic influenza (H1N1) virus by real-time reverse-transcriptase polymerase chain reaction (RT-PCR). He received oseltamivir (150 mg/day) for 5 days. A day after completing the oseltamivir therapy, his proteinuria returned to a normal range; urinalysis was negative for protein with PCR 79.2 mg/g. One month later, the patient remained normal with no proteinuria.
PMID:
22116504
[PubMed - as supplied by publisher]
Relapse of minimal change disease following infection with the 2009 pandemic influenza (H1N1) virus.
Kim SR, Lee SB, Kim IY, Lee DW, Rhee H, Seong EY, Song SH, Kwak IS.
Source
Division of Nephrology, Department of Internal Medicine, Pusan National University School of Medicine, Beomeo-ri, Mulgeum-eup, Yangsan, Gyeongsangnam-do, 626-770, South Korea.
Abstract
We report a case of relapse of minimal change disease following infection with the influenza A (H1N1) virus responsible for the 2009 pandemic. A 22-year-old man who had been diagnosed with minimal change disease presented with systemic edema. He had achieved complete remission with an oral steroid (prednisolone 1 mg/kg/day) by the 17th day of administration. On the 27th day of prednisolone administration, he presented with a new onset of generalized edema after several days of productive coughing. His urine showed proteinuria (4+) with a protein/creatinine ratio (PCR) of 2852.1 mg/g. His nasal swab sample was positive for the 2009 pandemic influenza (H1N1) virus by real-time reverse-transcriptase polymerase chain reaction (RT-PCR). He received oseltamivir (150 mg/day) for 5 days. A day after completing the oseltamivir therapy, his proteinuria returned to a normal range; urinalysis was negative for protein with PCR 79.2 mg/g. One month later, the patient remained normal with no proteinuria.
PMID:
22116504
[PubMed - as supplied by publisher]
