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J Pediatr. 2011 Nov 16. [Epub ahead of print]
2009 Influenza A in Infants Hospitalized at Younger than 6 Months.
Lopez-Medina E, Ardura MI, Siegel JD, Brock E, S?nchez PJ.
Source
Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX.
Abstract
OBJECTIVE:
To describe the clinical characteristics and outcomes of infants hospitalized at <6 months of age with 2009 influenza A infection.
STUDY DESIGN:
Prospective laboratory surveillance and discharge International Classification of Disease, 9th edition codes for influenza infection were used to identify all infants hospitalized at <6 months of age with positive influenza A tests at Children's Medical Center Dallas from April 27, 2009 to March 23, 2010. Retrospective chart review then was performed.
RESULTS:
Seventy-three infants aged <6 months were hospitalized with laboratory-confirmed influenza A infection at a median age of 48 days (range, 3-179 days). The most common clinical characteristics were fever and respiratory signs, and 53% were given a bolus of intravenous fluid. Median length of hospitalization was 2 days (range, 1-162 days). Twenty (27%) infants developed influenza-related complications, including pneumonia (n = 3), hypoxia (n = 18), seizures (n = 2), need for intensive care (n = 8), or death (n = 2). Oseltamivir was administered to 60 (82%) infants and was well tolerated.
CONCLUSIONS:
The majority of infants hospitalized with 2009 influenza A had community-acquired infection that was associated with short hospital stays and favorable short-term outcomes. Complications including death occurred, emphasizing the need for preventive strategies.
Copyright ? 2011 Mosby, Inc. All rights reserved.
PMID:
22099687
[PubMed - as supplied by publisher]
2009 Influenza A in Infants Hospitalized at Younger than 6 Months.
Lopez-Medina E, Ardura MI, Siegel JD, Brock E, S?nchez PJ.
Source
Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX.
Abstract
OBJECTIVE:
To describe the clinical characteristics and outcomes of infants hospitalized at <6 months of age with 2009 influenza A infection.
STUDY DESIGN:
Prospective laboratory surveillance and discharge International Classification of Disease, 9th edition codes for influenza infection were used to identify all infants hospitalized at <6 months of age with positive influenza A tests at Children's Medical Center Dallas from April 27, 2009 to March 23, 2010. Retrospective chart review then was performed.
RESULTS:
Seventy-three infants aged <6 months were hospitalized with laboratory-confirmed influenza A infection at a median age of 48 days (range, 3-179 days). The most common clinical characteristics were fever and respiratory signs, and 53% were given a bolus of intravenous fluid. Median length of hospitalization was 2 days (range, 1-162 days). Twenty (27%) infants developed influenza-related complications, including pneumonia (n = 3), hypoxia (n = 18), seizures (n = 2), need for intensive care (n = 8), or death (n = 2). Oseltamivir was administered to 60 (82%) infants and was well tolerated.
CONCLUSIONS:
The majority of infants hospitalized with 2009 influenza A had community-acquired infection that was associated with short hospital stays and favorable short-term outcomes. Complications including death occurred, emphasizing the need for preventive strategies.
Copyright ? 2011 Mosby, Inc. All rights reserved.
PMID:
22099687
[PubMed - as supplied by publisher]
