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Impact of the 2009/2010 influenza A (H1N1) pandemic on trends in influenza hospitalization, diagnostic testing, and treatment

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  • Impact of the 2009/2010 influenza A (H1N1) pandemic on trends in influenza hospitalization, diagnostic testing, and treatment

    Influenza Other Respi Viruses. 2011 Nov 16. doi: 10.1111/j.1750-2659.2011.00303.x. [Epub ahead of print]
    Impact of the 2009/2010 influenza A (H1N1) pandemic on trends in influenza hospitalization, diagnostic testing, and treatment.
    Hernandez JE, Grainger J, Simonsen L, Collis P, Edelman L, Sheridan WP.
    Source

    BioCryst Pharmaceuticals, Durham, NC, USA Department of Global Health, George Washington University, Washington, DC, USA SDI Health, LLC, Plymouth Meeting, PA, USA.
    Abstract

    Please cite this paper as: Hernandez et al. (2011) Impact of the 2009/2010 influenza A (H1N1) pandemic on trends in influenza hospitalization, diagnostic testing, and treatment. Influenza and Other Respiratory Viruses DOI: 10.1111/j.1750-2659.2011.00303.x. Analysis of a US hospitalization database demonstrated that more influenza patients were hospitalized and the age distribution of hospitalizations was younger during the 2009 (H1N1) influenza A pandemic compared with the three previous influenza seasons. The duration of hospital stay remained stable in all four seasons. A higher proportion of patients was treated with antivirals (P < 0?0001), comprised almost entirely of neuraminidase inhibitors, and the proportion was highest in those with influenza confirmed by diagnostic testing (P < 0?0001). Approximately one-third remained untreated. Young children had the lowest rate of neuraminidase-inhibitor treatment during the 2009 pandemic (P < 0?05).

    ? 2011 Blackwell Publishing Ltd.

    PMID:
    22085222
    [PubMed - as supplied by publisher]

    Analysis of a US hospitalization database demonstrated that more influenza patients were hospitalized and the age distribution of hospitalizations was younger during the 2009 (H1N1) influenza A pandemic compared with the three previous influenza seasons. The duration of hospital stay remained stable …
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