Favipiravir and Zanamivir Cleared Infection with Influenza B in a Severely Immunocompromised Child - FluTrackers News and Information

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Favipiravir and Zanamivir Cleared Infection with Influenza B in a Severely Immunocompromised Child

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tetano

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Join Date: Dec 2009

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Favipiravir and Zanamivir Cleared Infection with Influenza B in a Severely Immunocompromised Child

March 7, 2020, 02:18 AM

Clin Infect Dis. 2020 Mar 3. pii: ciaa023. doi: 10.1093/cid/ciaa023. [Epub ahead of print] Favipiravir and Zanamivir Cleared Infection with Influenza B in a Severely Immunocompromised Child.

Lumby CK¹, Zhao L¹, Oporto M², Best T², Tutill H³, Shah D³, Veys P², Williams R³, Worth A², Illingworth CJR^1,⁴, Breuer J^2,³.
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Abstract

A combination of favipiravir and zanamivir successfully cleared influenza B infection in a child who had undergone bone marrow transplant for X-linked severe combined immunodeficiency, with no recovery of T lymphocytes. Deep sequencing of viral samples illuminated the within-host dynamics of infection, demonstrating the effectiveness of favipiravir in this case.
? The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

KEYWORDS:

favipiravir; genome sequencing; influenza; zanamivir

PMID: 32124919 DOI: 10.1093/cid/ciaa023

Tags: None

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