Tweet
Biochimie. 2017 Aug 1. pii: S0300-9084(17)30187-6. doi: 10.1016/j.biochi.2017.07.016. [Epub ahead of print]
TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections.
Shen LW1, Mao HJ1, Wu YL2, Tanaka Y3, Zhang W4.
Author information
Abstract
Influenza virus and coronavirus epidemics or pandemics have occurred in succession worldwide throughout the early 21st century. These epidemics or pandemics pose a major threat to human health. Here, we outline a critical role of the host cell protease TMPRSS2 in influenza virus and coronavirus infections and highlight an antiviral therapeutic strategy targeting TMPRSS2.
Copyright ? 2017. Published by Elsevier B.V.
KEYWORDS:
Coronavirus; Influenza virus; TMPRSS2; Therapeutics
PMID: 28778717 DOI: 10.1016/j.biochi.2017.07.016
TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections.
Shen LW1, Mao HJ1, Wu YL2, Tanaka Y3, Zhang W4.
Author information
Abstract
Influenza virus and coronavirus epidemics or pandemics have occurred in succession worldwide throughout the early 21st century. These epidemics or pandemics pose a major threat to human health. Here, we outline a critical role of the host cell protease TMPRSS2 in influenza virus and coronavirus infections and highlight an antiviral therapeutic strategy targeting TMPRSS2.
Copyright ? 2017. Published by Elsevier B.V.
KEYWORDS:
Coronavirus; Influenza virus; TMPRSS2; Therapeutics
PMID: 28778717 DOI: 10.1016/j.biochi.2017.07.016