Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA - FluTrackers News and Information

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Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA

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Shiloh

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Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA

February 13, 2019, 06:19 PM

Source: https://wwwnc.cdc.gov/eid/article/25/3/18-0960_article

Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA1

Christopher J. HarrisonComments to Author , William C. Weldon2, Barbara A. Pahud2, Mary Anne Jackson2, M. Steven Oberste2, and Rangaraj Selvarangan2
Author affiliations: The Children?s Mercy Hospital, Kansas City, Missouri, USA (C.J. Harrison, B.A. Pahud, M.A. Jackson, R. Selvarangan); University of Missouri at Kansas City, Kansas City (C.J. Harrison, B.A. Pahud, M.A. Jackson, R. Selvarangan); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (W.C. Weldon, M.S. Oberste)

Abstract

We evaluated enterovirus D68 seroprevalence in Kansas City, Missouri, USA, from samples obtained during 2012?2013. Neutralizing antibodies against Fermon and the dominant 2014 Missouri isolate were universally detected. Titers increased with age. Widespread circulation of enterovirus D68 occurred before the 2014 outbreak. Research is needed to determine a surrogate of protection...

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