Clarksville man may be 12th Tennessee flu death

[Shiloh]

Source: http://www.theleafchronicle.com/arti...nclick_check=1


Clarksville man may be 12th Tennessee flu death
Church deacon died Jan. 3 from complications
Jan. 11, 2014 6:17 PM

CLARKSVILLE, TENN. ? A Clarksville man may be the 12th Tennessean to die from flu-related causes this season.

According to a report from Leaf-Chronicle news partner WSMV, Ken Harris of Clarksville passed away Jan. 3 due to complications from the flu.

Harris, owner of Harris Woodworks in Sango and a deacon of Hilldale Church of Christ, was 49...

[NS1]

Re: Clarksville man may be 12th Tennessee flu death

pH1N1 Genetic Sequence
Sparsity
for
Tennessee

Only two genetic sequences are on file from Tennessee during 2013 with none after March. Those distant sequences suggest a circulation pattern similar to Texas and New Mexico.

Texas communicated two TamiFlu Resistant cases in this week's Public Health report.

[NS1]

Re: Clarksville man may be 12th Tennessee flu death

pH1N1 Child Vaccine Escape
CDC Early 2013

Map - Active and Detailed

<div style="text-align: center;">
<hr style="width: 30%;" />41 Cases over 43 Sequences<hr style="width: 30%;" /></div>
Introduction

In the 30 days covering 2013-02-28 to 2013-03-29, the&nbsp;<span style="color: #783f04;"><b>United States CDC</b></span>&nbsp;released a total of 43&nbsp;<b><span style="color: #632423; font-family: &quot;Trebuchet MS&quot;;">pH1N1</span></b>&nbsp;sequences at&nbsp;<strong>GISAID&nbsp;</strong>on 41 human cases<strong>&nbsp;</strong>sampled from October 2012 to February 2013. Geographic surveillance includes&nbsp;<b>America,</b>&nbsp;<b>Africa, Asia </b>and<b> Russia.&nbsp;</b>Although&nbsp;<b><span style="color: #632423; font-family: &quot;Trebuchet MS&quot;;">pH1N1</span></b>&nbsp;in most locales during the&nbsp;2012-2013 season was the <b><span style="color: #783f04;">minority</span></b> serotype, the sequences in this Analytic Report describe a high level of human-infective diversity and an ease of avian genetic acquisition, including multiple instances demonstrating concentrated transport of <b><span style="color: #660000;">High-CFR</span></b>&nbsp;<b><span style="color: #632423; font-family: &quot;Trebuchet MS&quot;;">pH1N1&nbsp;</span><span style="color: #783f04;">Upsilon</span></b> polymorphisms onto single sequences.

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Read the Open-Access, Full-Text
Investigational Analytic
including Genetic Details

[NS1]

Re: Clarksville man may be 12th Tennessee flu death

pH1N1 Genetic Sequence
Sparsity
for
Tennessee

Only two genetic sequences are on file from Tennessee during 2013 with none after March. Those distant sequences suggest a circulation pattern similar to Texas and New Mexico.

pH1N1 TamiFlu Resistance

The most recent Tennessee sequence, sampled from a 53 year old woman in March 2013, is Drug Resistant (TmX275 onto a very common Neuraminidase) and displays CrossClade tendencies with Emergent H7N9 homology on the Hemagglutinin.

The Neuraminidase lineage is common; The CrossClade Hemagglutinin lineage was widespread to geographies supporting avian inclusions, e.g. Brazil [EPI484739] and Costa Rica [EPI484980].