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Re: Queens tot suspected to be second swine flu death in New York City
Child died in Queens did not have influenza H1N1
05/20/09
The analysis carried out in an infant who died after being hospitalized in New York with respiratory problems are not suffering from swine flu, health officials said the city.
A Health Department statement said the analysis made on samples taken from nasal* boy 16 months, Jonathan Zamora Castillo.
SNIP
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* Nasal Swab Test (a/k/a RAPID H1N1 INFLUENZA TEST)
excerpt from:
CDC GUIDLINES AS TO RELIABILITY OF RAPID H1N1 INFLUENZA TEST
Reliability and Interpretation of Rapid Influenza Test Results
The reliability of rapid influenza diagnostic tests depends largely on the conditions under which they are used, and are entirely based on the experience with seasonal influenza.
For detection of seasonal influenza virus infection, sensitivities of rapid diagnostic tests are approximately 50-70% when compared with viral culture or RT-PCR, and specificities of rapid diagnostic tests for influenza are approximately 90-95%. Sensitivity and specificity of these tests for detection of the novel H1N1 flu virus are unknown.
False-positive (and true-negative) results are more likely to occur when influenza is uncommon in the community, which is generally at the beginning and end of an outbreak.
False-negative (and true-positive) results are more likely to occur when influenza is common in the community, which is typically at the height of an outbreak.
Test sensitivity may vary depending on when in the course of illness the specimen is collected. Respiratory specimens for testing should be collected in the first 4-5 days of illness when viral shedding is greatest. Given these limitations, the decision of whether or not to test patients with rapid influenza diagnostic tests should be based upon the patient’s presenting symptoms, whether or not cases of novel H1N1 have been confirmed in the area, and/or the patient’s risk for severe disease or other complications.
Child died in Queens did not have influenza H1N1
05/20/09
The analysis carried out in an infant who died after being hospitalized in New York with respiratory problems are not suffering from swine flu, health officials said the city.
A Health Department statement said the analysis made on samples taken from nasal* boy 16 months, Jonathan Zamora Castillo.
SNIP
____
* Nasal Swab Test (a/k/a RAPID H1N1 INFLUENZA TEST)
excerpt from:
CDC GUIDLINES AS TO RELIABILITY OF RAPID H1N1 INFLUENZA TEST
Reliability and Interpretation of Rapid Influenza Test Results
The reliability of rapid influenza diagnostic tests depends largely on the conditions under which they are used, and are entirely based on the experience with seasonal influenza.
For detection of seasonal influenza virus infection, sensitivities of rapid diagnostic tests are approximately 50-70% when compared with viral culture or RT-PCR, and specificities of rapid diagnostic tests for influenza are approximately 90-95%. Sensitivity and specificity of these tests for detection of the novel H1N1 flu virus are unknown.
False-positive (and true-negative) results are more likely to occur when influenza is uncommon in the community, which is generally at the beginning and end of an outbreak.
False-negative (and true-positive) results are more likely to occur when influenza is common in the community, which is typically at the height of an outbreak.
Test sensitivity may vary depending on when in the course of illness the specimen is collected. Respiratory specimens for testing should be collected in the first 4-5 days of illness when viral shedding is greatest. Given these limitations, the decision of whether or not to test patients with rapid influenza diagnostic tests should be based upon the patient’s presenting symptoms, whether or not cases of novel H1N1 have been confirmed in the area, and/or the patient’s risk for severe disease or other complications.
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