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P&I up to 7.7% second highest in the last 10 years.
Four influenza-associated pediatric deaths were reported to CDC during week 51 (Florida [2], Massachusetts, and Texas). Two of these deaths were associated with 2009 influenza A (H1N1) virus infection and two were associated with an influenza A virus for which the subtype is undetermined. The deaths reported during week 51 occurred between August 30 and December 19, 2009.
Since August 30, 2009, CDC has received 225 reports of influenza-associated pediatric deaths that occurred during the current influenza season (42 deaths in children less than 2 years old, 25 deaths in children 2-4 years old, 83 deaths in children 5-11 years old, and 75 deaths in children 12-17 years old). One hundred eighty-three (81%) of the 225 deaths were due to 2009 influenza A (H1N1) virus infections, 41 were associated with influenza A virus for which the subtype is undetermined, and one was associated with an influenza B virus infection. A total of 243 deaths in children associated with 2009 influenza A (H1N1) virus infection have been reported to CDC.
Synopsis:
During week 51 (December 20-26, 2009), influenza activity decreased slightly in the U.S.
?154 (3.9%) specimens tested by U.S. World Health Organization (WHO) and National Respiratory and Enteric Virus Surveillance System (NREVSS) collaborating laboratories and reported to CDC/Influenza Division were positive for influenza.
?All subtyped influenza A viruses reported to CDC were 2009 influenza A (H1N1) viruses.
?The proportion of deaths attributed to pneumonia and influenza (P&I) was above the epidemic threshold.
?Four influenza-associated pediatric deaths were reported. Two of these deaths were associated with 2009 influenza A (H1N1) virus infection and two were associated with an influenza A virus for which the subtype was undetermined.
?The proportion of outpatient visits for influenza-like illness (ILI) was 3.2% which is above the national baseline of 2.3%. Two of the 10 regions (1 and 10) reported ILI below region-specific baseline levels.
?o Four states reported geographically widespread influenza activity, 13 states reported regional influenza activity, the District of Columbia, Puerto Rico, and 19 states reported local influenza activity, Guam and 13 states reported sporadic influenza activity, and one state reported no influenza activity, the U.S. Virgin Islands did not report.
Deaths per million based on state's population by region (lowest and highest states are listed...other states within region fall in between these numbers) Of note, MO seems an unrealistic number, and perhaps should be ignored. while NM is highest, and perhaps they have better reporting. Additionally, within Region 8, ND shows 4.7 while SD is 28.6 with that region having highest H1N1 cases in the nation.
........death rate per million......case rate per million
Region 1: ME (4.2-13.7) MA .......446.3
Region 2: NJ (4.8-13.7) PR .........97.3
Region 3: VA (4.9-11) WV .........555.6
Region 4: GA (4.2-10.7) FL ........271.9
Region 5: OH (3.6-10.9) MN .......362.1
Region 6: AR (7.3-25.7) NM .......219.5
Region 7: MO (1.9-13.3) IA ........390.5
Region 8: ND (4.7-28.6) SD ......1160.1
Region 9: HI (8.5-21) AZ ...........352.6
Region10: ID (13.1-19.8) OR ......620.2
USA: 9.7
Yesterday on the radio show I asked Dr. Racaniello if we should watch the fiqure below (0.3%) to increase as a sign that the current vaccine is becoming less effective and he said "yes". He expects slowly over time we will need a new vaccine to replace the current one. He says that from all the data he has seen that the current vaccine is still very effective.
"Two viruses (0.3%) tested showed reduced titers with antiserum produced against A/California/07/2009."
Based on the antigenic characterization of 799 influenza viruses reported from week 40/2009 to week 52/2009, 792 were pandemic A(H1N1), A/California/7/2009-like, 3 were A/Perth/16/2009 (H3N2)-like, 2 were A(H3) A/Brisbane/10/2007 (H3N2)-like, 1 was A/Brisbane/59/2007 (H1N1)-like, and 1 was B/Brisbane/60/2008-like. Genetic characterizations were available for 252 isolates; all belonged to the A/California/7/2009 A(H1N1) pandemic influenza lineage.
even if the virus mutates away, the vax would still be effective in the sense, that it
converts pandemic outbreaks into seasonal ones. The 1976-vax is still somehow effective
vaccine is not so often changes, this one may be in use for 5 years or such, since it's a new virus.
Like New Caledonia/1999
The age stucture of states will have an effect on infection rates.
Additionally, don't underestimate the effects of variable detection of cases. States vary greatly in resources, capabilities, reporting methods and procedures.
See Missouri "Show Me" data. We hide behind our P&I.
Here's another way we do things: "No specimens were received by the State Public Health Laboratory for viral testing during week 52."
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