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Colorado state health officials confirm 9 cases of H5 & H5N1 avian flu in Colorado poultry workers (and one dairy worker = 10 (total for state) - July 12+

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  • #16
    .....
    Sweltering barns, feathers flying



    Around 160 workers inside barns at the facility were tasked with pulling out chickens, placing several at a time in a cart that would then be filled with carbon dioxide, killing them in under a minute-and-a-half, Dr. Julie Gauthier, the USDA's executive director for field operations in the Animal and Plant Health Inspection Service, said on the call.

    ​​​​​​

    Temperatures in northeast Colorado have hit 104 degrees, though Shah said temperatures inside the barns were even hotter. Workers wore light paper protective suits over their clothes, N95 respirators, goggles, boots and gloves. Industrial fans pushed air through the barns.

    The fans made it uncomfortable to wear PPE, all while feathers ‒ a means in which bird flu virus can spread ‒ blew around. This likely caused the infections in five workers, officials said.

    This suggests that risks can be better controlled in the future with more systematic use of PPE, in addition to measures to improve ventilation, Shah said. A 10-person CDC team, which includes bilingual speakers and an industrial hygienist, arrived in Colorado on Saturday to monitor and test workers and suggest safety improvements.

    In total, 60 workers were tested for bird flu, with 55 testing negative, though many had symptoms consistent with other respiratory illnesses like rhinovirus, Shah said.

    Sixteen workers who are symptomatic had been tested Monday, said AnneMarie Harper, a spokesperson for the Colorado Department of Public Health and Environment, in an email. Testing remains ongoing and Shah said more infections might come to light.....


    There is no recommendation yet for people to receive the vaccine, which has not been fully tested or approved for use.

    The agency also distributed 5,000 goggles, 300,000 gloves, 150,000 N95 masks and 528 courses of Tamiflu to Colorado, Boucher said....




    CSI:WORLD http://swineflumagazine.blogspot.com/

    treyfish2004@yahoo.com

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    • #17
      Heat was likely a factor in 5 human bird flu infections in Colorado
      ...
      By Staff Author Published on July 16, 2024
      ...
      It’s believed they were each infected by egg-laying chickens as they sought to cull a flock of about 1.8 million in the northeast part of the state.

      It is customary to kill entire flocks when they are infected by highly pathogenic avian influenza — which readily infects and kills poultry — to prevent its spread to other flocks.

      The Colorado workers grabbed the chickens, placed them into containers that can hold dozens at a time, and asphyxiated them with carbon dioxide, said Dr. Julie Gauthier, executive director for field operations for the U.S. Department of Agriculture’s Animal and Plant Health Inspection Service.

      The workers typically wear suits, goggles, gloves and boots, and they breathe through respirators that protect them from pathogens.

      But the outdoor temperature at the time of the work was about 100 degrees, and the temperature inside the facility was likely hotter. Giant fans moved air to cool the inside, which circulated potentially virus-laden debris such as feathers.

      “The difficulty with wearing all that gear in that kind of heat, you can imagine,” Gauthier said, “and it was made more difficult by those fans pushing the air — made it hard to keep those goggles and N95 respirators in place.”

      The virus that infected the flock is similar to one that has infected dairy cattle in 13 states, Shah said. Colorado has had the most infected herds of any state, with at least 37. It’s possible that the virus was transported to the egg-laying flock from one of those herds, Shah said.
      ...

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      • #18
        CDC A(H5N1) Bird Flu Response Update, July 19, 2024
        ...​
        Finally, we confirm in today’s Spotlight two additional cases of avian influenza in Colorado poultry farm workers. There was a recent poultry outbreak on the farm with human cases that were exposed to the virus related to a culling of birds, and we have confirmed H5N1 infection in six poultry workers from that event. The infected workers have all experienced mild symptoms, and workers exposed to the virus have been offered antiviral medication.
        ​...
        Since April 2024, 10 human cases of avian influenza A(H5) infection have been reported in the United States. Four of these cases were associated with exposure to sick dairy cows and six were associated with exposure to H5N1-infected poultry.* [A][B] This includes two additional cases in Colorado that were confirmed by CDC this week and not previously reported. The two new cases were in poultry workers with exposure to infected poultry during depopulation and disposal activities. Similar to previous cases, illness was mild. Based on the information available at this time, CDC’s current H5N1 bird flu human health risk assessment for the U.S. general public remains low.
        ...
        Among other activities previously reported in past spotlights and still ongoing, recent highlights of CDC's response to this include:
        ...
        • Keeping in close contact with a CDC multidisciplinary bilingual field team of 10 people deployed to support Colorado’s response to ongoing poultry outbreaks. The team includes epidemiologists, veterinarians, clinicians and an industrial hygienist. Support includes accompanying Colorado health officials during daily visits to the affected farm to monitor workers for symptoms, test symptomatic persons, dispense antiviral treatment, follow-up with persons testing positive to collect additional information, and assess use of personal protective equipment.
        • Posting the sequence of the influenza virus genome from a positive specimen collected from one patient in Colorado participating in an A(H5N1) infected poultry farm depopulation (A/Colorado/109/2024) to GISAID (EPI_ISL_19263923) and GenBank (PQ032835). CDC sequenced the influenza virus genome, confirming the neuraminidase (the N in the subtype) is an N1 and the virus is a HPAI A(H5N1) virus from clade 2.3.4.4b. An analysis of the sequence indicates:
          • This virus is genotype B3.13 clade 2.3.4.4b HPAI A(H5N1) with each individual gene segment closely related to viruses detected in recent poultry outbreaks and infected dairy cattle herds made available from USDA. Among human virus sequences, A/Colorado/109/2024 is most similar to the genome of the human case in Michigan.
            • The sequence maintains primarily avian genetic characteristics and lacks changes that would make the virus better adapted to infect or spread among humans.
            • The sequence contains a change at PB2 M631L – which is the same marker of mammalian adaptation identified in >99% dairy cow sequences and that was also identified in the first Michigan human case.
            • The genome does NOT have the PB2 E627K change that was seen in the virus from the case in Texas, but not subsequent human viruses. (That change is known to be associated with viral adaptation to mammalian hosts and has been found before in people and other mammals, but with no evidence of onward spread among people.)
            • Furthermore, there are no markers known to be associated with influenza antiviral resistance found in the virus sequences from the patient's specimen.
          • This is the only virus that CDC has been able to fully sequence out of the cases in Colorado so far. Partial gene segments were obtained from two of the other confirmed human cases associated with the poultry farm depopulation. Only internal genes (not HA and NA) generated sufficient data for analysis to date. This data confirmed identical gene sequences among the CO cases based on available data.
          • The HA sequence of the Colorado poultry worker virus is very closely related (only 2 or 4 amino acid changes) to two existing HPAI A(H5) candidate vaccine viruses [IDCDC-RG78A (A/American Wigeon/South Carolina/22-000345-001/2021-like) and IDCDC-RG71A (A/Astrakhan/3212/2020-like), respectively] that are already available to manufacturers, and which could be used to make vaccine if needed.
          • There are no changes to the virus that would suggest the risk to human health has increased.
          • Overall, the genetic analysis of the HPAI A(H5N1) virus in Colorado supports CDC's conclusion that the human health risk currently remains low.
        ​...

        CDC provides a response activities update on the multistate outbreak of H5 bird flu in dairy cows.

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        • #19
          Another case of avian flu in Weld County brings total to 7


          ​​​​​​https://www.youtube.com/watch?app=desktop&v=qBdQPV3uZrw
          CSI:WORLD http://swineflumagazine.blogspot.com/

          treyfish2004@yahoo.com

          Comment


          • #20
            The Colorado Department of Public Health and Environment has not updated their website to reflect the 7th case yet.

            Comment


            • #21
              Seventh poultry worker in Colorado with bird flu


              July 21, 2024

              An additional worker became infected with the H5N1 avian flu virus while culling sick hens at a Colorado egg farm, said state public health officials, raising the U.S. total of infected workers to 11, all with mild symptoms. Eight of the cases, seven involving poultry and one involving dairy, have occurred in Colorado. The Centers.

              CSI:WORLD http://swineflumagazine.blogspot.com/

              treyfish2004@yahoo.com

              Comment


              • #22
                State health officials closely monitor farms responding to avian flu spread in poultry and cows

                State health officials report another presumptive case of avian flu in a poultry farm worker

                Denver (July 20, 2024) — State health officials have identified another presumptive positive human case of avian flu after providing assistance at a second poultry farm in northeast Colorado/Weld County. The State Laboratory will now send the sample to the Centers for Disease Control and Prevention for confirmation. Testing of other workers, who are culling infected poultry at the commercial egg layer operation, is ongoing.

                For detailed information on previous cases and the state's ongoing response, please refer to our earlier press release(opens in new window), which reports six confirmed human cases of avian flu among workers at another farm in Weld County.

                The state’s disciplined, coordinated response between the Colorado Department of Agriculture, Colorado Department of Public Health and Environment, and the State Emergency Operations Center allows it to respond quickly to farms across Colorado.

                The CDC continues to state that the risk of avian flu to the general public is low. It also continues to be safe to consume properly handled and cooked poultry products. For more information about avian flu in humans, visit CDPHE's avian flu information page(opens in new window).

                Comment


                • #23
                  Seventh poultry worker in Colorado with bird flu


                  The Centers for Disease Control said the risk to the general public from the disease is low.

                  By
                  FERN's Ag Insider


                  Published on July 22, 2024
                  An additional worker became infected with the H5N1 avian flu virus while culling sick hens at a Colorado egg farm, said state public health officials, raising the U.S. total of infected workers to 11, all with mild symptoms. Eight of the cases, seven involving poultry and one involving dairy, have occurred in Colorado.

                  The Centers for Disease Control said the risk to the general public from the disease is low. It recommends use of protective equipment, such as goggles, masks and gloves, by people in contact with infected or possibly infected animals.

                  The Colorado Department of Public Health and Environment said six workers, one more than reported earlier, contracted bird flu while killing and disposing of H5N1-infec
                  ​....

                  ​​​​​​https://www.agriculture.com/seventh-...rd-flu-8681340
                  CSI:WORLD http://swineflumagazine.blogspot.com/

                  treyfish2004@yahoo.com

                  Comment


                  • #24
                    Colorado: 3 Confirmed Human H5 Infections at 2nd Poultry Farm






                    #18,207

                    Today Colorado's Health Department announced 3 confirmed cases of HPAI H5 among poultry workers on the 2nd farm (one case was reported as presumed positive on Monday), bringing to 10 the number of cases (1 cattle linked, 9 poultry linked) reported by that state over the past few months.

                    No details are provided on these 2 new cases, with the thrust of the announcement focused more on the unveiling - later today - of a new data table for tracking cases. We should get more details tomorrow, however, from the CDC weekly roundup.

                    The brief statement follows.

                    Coloradans can find twice weekly updates on avian flu in humans on the CDPHE website

                    Denver (July 25, 2024) — The Colorado Department of Public Health and Environment — in coordination with the Colorado Department of Agriculture and State Emergency Operations Center — is reporting three confirmed cases of avian flu in humans at a second farm in Weld County, bringing the total number of cases to three at that particular farm. Public health officials first reported news of the virusat a second farm last Saturday. This update brings Colorado's total number of confirmed avian flu cases in humans to 10 — nine cases at two poultry farms and one case from a dairy farm.

                    Later today, the Colorado Department of Public Health and Environment will launch a data table to track cases of avian flu in humans. The table will be updated on the CDPHE websiteby 4 p.m. every Tuesday and Thursday.

                    The biweekly update will include the number of presumptive positive human cases, number of confirmed human cases, approximate number of people tested, and a link to the Colorado Department of Agriculture for the number of impacted dairy and poultry farms.

                    The
                    Colorado Department of Agriculture provides data on avian flu in poultry and dairy cattle, which is updated weekly or as data is confirmed.

                    The CDC continues to state that the risk of avian flu to the general public is low. So far, we have not seen evidence of person-to-person transmission. Epidemiologists both here in Colorado and at CDC are monitoring for genetic variations in the virus and changes in transmission patterns.


                    It seems likely that more cases will turn up in the days and weeks ahead.

                    Stay tuned.​

                    All medical discussions are for educational purposes. I am not a doctor, just a retired paramedic. Nothing I post should be construed as specific medical advice. If you have a medical problem, see your physician.

                    Comment


                    • #25
                      State health officials to publish data table for human cases of avian flu in Colorado

                      Coloradans can find twice weekly updates on avian flu in humans on the CDPHE website

                      Denver (July 25, 2024) — The Colorado Department of Public Health and Environment — in coordination with the Colorado Department of Agriculture and State Emergency Operations Center — is reporting three confirmed cases of avian flu in humans at a second farm in Weld County, bringing the total number of cases to three at that particular farm. Public health officials first reported news of the virus at a second farm last Saturday. This update brings Colorado's total number of confirmed avian flu cases in humans to 10 — nine cases at two poultry farms and one case from a dairy farm.

                      Later today, the Colorado Department of Public Health and Environment will launch a data table to track cases of avian flu in humans. The table will be updated on the CDPHE website by 4 p.m. every Tuesday and Thursday.

                      The biweekly update will include the number of presumptive positive human cases, number of confirmed human cases, approximate number of people tested, and a link to the Colorado Department of Agriculture for the number of impacted dairy and poultry farms.

                      The Colorado Department of Agriculture provides data on avian flu in poultry and dairy cattle, which is updated weekly or as data is confirmed.

                      The CDC continues to state that the risk of avian flu to the general public is low. So far, we have not seen evidence of person-to-person transmission. Epidemiologists both here in Colorado and at CDC are monitoring for genetic variations in the virus and changes in transmission patterns.



                      ###

                      Las autoridades de salud estatales publican un tablero de datos sobre los casos humanos de gripe aviar en Colorado


                      Los coloradenses podrán encontrar dos veces por semana datos actualizados sobre casos de gripe aviar en seres humanos en el sitio web del CDPHE

                      Denver (25 de julio de 2024) — El Departamento de Salud Pública y Medio Ambiente de Colorado (CDPHE) — en tarea coordinada con el Departamento de Agricultura de Colorado y el Centro Estatal de Operaciones de Emergencia — notifica tres casos confirmados de gripe aviar en una segunda granja del Condado de Weld, lo cual lleva el total de casos en dicha granja a tres. Los funcionarios de Salud Pública informaron acerca de la presencia del virus en esta segunda granja el pasado sábado. Con esta actualización, el número total de caso de gripe aviar en seres humanos se eleva a diez (nueve en dos granjas avícolas y uno en un establecimiento lechero).

                      Más tarde durante el día de hoy, el CDPHE lanzará un tablero de datos con el fin de rastrear los casos de gripe aviar en seres humanos. El tablero se actualizará en el sitio web del CDPHE antes de las 4 p.m. todos los martes y jueves.

                      La actualización quincenal incluirá el número de casos humanos presuntamente positivos y de casos confirmados, el número aproximado de pruebas de detección realizadas y un enlace al Departamento de Agricultura de Colorado para encontrar el número de establecimientos lecheros y granjas avícolas afectadas.

                      Los CDC continúan afirmando que el riesgo de contagio es bajo para el público en general. A la fecha, no hemos encontrado evidencia de transmisión entre seres humanos. Los epidemiólogos del Estado de Colorado y de los CDC están monitoreando variaciones genéticas en el virus y modificaciones en el mecanismo de transmisión.​


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                      • #26
                        Please see:

                        US - H5N1 Human Case List

                        Comment


                        • #27
                          3 Colorado poultry workers at second egg facility test positive for bird flu, bringing state total to 10

                          CDPHE to launch bird flu human tracker as cases among people continue to increase
                          Posted at 1 hour and 32 minutes ago
                          and last updated 0 minutes ago
                          Óscar Contreras
                          …..


                          The update from the Colorado Department of Public Health and Environment (CDPHE) means nine workers have been infected with H5N1 at poultry farms — eight of them just within the past two weeks — since the outbreak of avian influenza was first detected in the state in March of 2022.

                          A dairy worker was infected with the virusearlier this month after coming into contact with sick cattle, the first instance in which the virus was likely transmitted from a mammal to a human since the unprecedented spillover of the virus into the country’s dairy cattle herds earlier this year.

                          The announcement from the CDPHE did not say what clinical symptoms the three additional poultry workers presented, nor did it say if any had to be hospitalized or what type of antiviral treatment they had received. Denver7 has reached out to the state health department for additional details.

                          A news release from the CDC, however, stated all three workers have mild illness and have been offered oseltamivir for treatment of their symptoms.

                          These three additional cases now bring the total number of humans infected with H5N1 since the virus was first detected in the U.S. in 2022 to 14, according to the CDC.

                          ​….
                          Three additional poultry workers at a second commercial egg-laying facility in Weld County affected by an outbreak of avian influenza have tested positive for bird flu, per state health officials
                          CSI:WORLD http://swineflumagazine.blogspot.com/

                          treyfish2004@yahoo.com

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                          • #28
                            CDC Confirms Three Human Cases of H5 Bird Flu Among Colorado Poultry Workers

                            ​For immediate release:
                            July 25, 2024​

                            STATEMENT

                            Media Statement - Three additional human cases of highly pathogenic avian influenza (HPAI) A(H5) (“H5 bird flu”) virus infection have been confirmed by the Centers for Disease Control and Prevention (CDC) in association with a second poultry farm in Northeast Colorado/Weld County.

                            July 25, 2024 – Three additional human cases of highly pathogenic avian influenza (HPAI) A(H5) (“H5 bird flu”) virus infection have been confirmed by the Centers for Disease Control and Prevention (CDC) in association with a second poultry farm in Northeast Colorado/Weld County. Colorado previously announced one of them as a presumptive positive case on Saturday, July 20. The three confirmed cases occurred in people who were working directly with infected poultry at a commercial egg layer operation that had reported an outbreak of H5 bird flu among poultry.

                            All three people have mild illness and have been offered the antiviral drug, oseltamivir, for treatment. State and local officials continue to monitor poultry workers on farms with infected poultry. This is a different farm in Colorado from the one where on Friday, July 19, CDC confirmed two additional human cases of H5 bird flu, which brought the total human cases associated with that first poultry farm to six. With the addition of these three new confirmed human cases, the total number of human cases associated with the current poultry outbreaks in Colorado is nine. A CDC multidisciplinary, bilingual field team is currently deployed to support Colorado’s response to ongoing poultry outbreaks of H5 bird flu in the state.

                            Confirmation of these three additional cases brings the total number of human cases of H5 bird flu reported in the United States since April 2024 to 13. Prior to 2024, the only previous human case of H5N1 bird flu in the United States was reported among a poultry worker in Colorado in April 2022. Counting that case, there have been 14 total human cases of H5 bird flu in the United States since 2022.

                            Based on available data, CDC’s current assessment is that the risk to the general public from H5N1 remains low. As we learn more, we will continue to assess the situation and provide updates. These preliminary results again underscore the risk of exposure to infected animals. There are no signs of unexpected increases in flu activity otherwise in Colorado, or in other states affected by H5 bird flu outbreaks in cows and poultry. Human infections with this novel influenza A virus (and others) are concerning because of the potential to cause severe, widespread disease. To date, we have not seen genetic changes in the virus that would make it more likely to transmit between humans, but we are closely monitoring it.

                            CDC’s recommendations related to H5 virus have not changed at this time. Findings from the investigation will inform whether guidance changes are needed. The investigation will include looking into compliance with the recommended use of personal protective equipment. Historically, most human cases of bird flu infection have happened in people who are not wearing recommended personal protective equipment. An analysis of the virus sequences from this outbreak also will be important to determine if a change in the risk assessment is warranted.

                            CDC Recommendations

                            • People should avoid unprotected exposures to sick or dead animals, including wild birds, poultry, other domesticated birds, and other wild or domesticated animals (including cows).

                            • People should also avoid unprotected exposures to animal feces (poop), bedding (litter), unpasteurized (“raw”) milk, or materials that have been touched by, or close to, birds or other animals with suspected or confirmed A(H5N1) virus.

                            • CDC has interim recommendations for prevention, monitoring, and public health investigations of A(H5N1) virus infections in people. CDC also has updated recommendations for worker protection and use of personal protective equipment (PPE). Following these recommendations is central to reducing a person’s risk and containing the overall public health risk.

                            Last edited by Pathfinder; July 26, 2024, 07:35 AM. Reason: Title

                            Comment


                            • #30
                              CDC A(H5N1) Bird Flu Response Update July 26, 2024
                              ...
                              CDC Update
                              ...
                              Since April 2024, 13 human cases of avian influenza A(H5) infection have been reported in the United States. Four of these cases were associated with exposure to sick dairy cows and nine were associated with exposure to avian influenza A(H5N1)-infected poultry. A B This includes three additional cases in Colorado that were confirmed by CDC this week. The three new cases were in poultry workers who were working directly with infected poultry at a commercial egg layer operation that had reported an outbreak of H5 bird flu among poultry. Similar to previous cases, all of the people have mild illness. Based on the information available at this time, CDC's current assessment is that the risk to the general public from H5 bird flu remains low. On the animal health side, USDA is reporting that 171 dairy cow herds in 13 U.S. states have confirmed cases of avian influenza A(H5N1) virus infections in dairy cows as the number of infected herds continues to grow. USDA reports that since April 2024, there have been A(H5) detections in 35 commercial flocks and 19 backyard flocks, for a total of 18.37 million birds affected.

                              Among other activities previously reported in past spotlights and ongoing, recent highlights of CDC's response to this include:

                              Colorado Investigation Update


                              More than 600 workers performing depopulation activities on three poultry farms have been screened for symptoms. Of these, 103 had symptoms and were tested, and nine were positive for influenza A(H5). Other respiratory viruses such as SARS-CoV-2 (the virus that causes COVID-19) were also detected among symptomatic workers. Symptom onset began within two-three days and peaked within five days after the start of depopulation. Among nine workers who tested positive for avian influenza A(H5), all reported mild symptoms (predominantly conjunctivitis) and were tested within three days of symptom onset. All cases have been provided oseltamivir and are recovering. More in-depth summaries of the investigation are in process with Colorado Department of Public Health and Environment.

                              Laboratory Update


                              CDC sequencing of the virus from the sixth human case reported from Colorado confirms the neuraminidase (the N in the subtype) is an N1 and the virus is a HPAI A(H5N1) virus from clade 2.3.4.4b. Six of the eight influenza virus gene segments (the majority of the flu genome) were successfully sequenced. The sequences are closely related to the virus sequence described last week, A/Colorado/109/2024, as well as viruses detected in recent poultry outbreaks and infected dairy cattle herds made available from USDA. The sequence maintains primarily avian genetic characteristics and lacks changes that would make the virus better adapted to infect or spread among humans.

                              The influenza virus sequence contains a change at PB2 M631L – which is the same marker of mammalian adaptation identified in more than 99% of dairy cow sequences and that was also identified in the first Michigan human case. The influenza virus sequence does NOT have the PB2 E627K change that was seen in the virus from the case in Texas but not subsequent human viruses. That change is known to be associated with viral adaptation to mammalian hosts and has been found before in people and other mammals, but with no evidence of onward spread among people.

                              Furthermore, there are no markers known to be associated with influenza antiviral resistance to neuraminidase-inhibitors found in the virus sequence from the patient's specimen. The genetic sequences for the virus from the patient (A/Colorado/134/2024) were posted to two sequence databases: GISAID (EPI_ISL_19280426) and GenBank (PQ060139). Influenza virus isolates and sequences were only successfully generated from two of the six human cases from the first poultry farm in Colorado. Overall, the genetic analysis of this HPAI A(H5N1) virus in Colorado supports CDC's conclusion that the human health risk currently remains low.

                              ...
                              https://flutrackers.com/forum/forum/national-international-government-ngo-preparation-response/cdc/h5n1-information/994336-cdc-a-h5n1-bird-flu-response-update-july-26-2024​

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